The first case of cobalamin deficiency with megaloblastic anaemia in a patient under long-term omeprazole therapy is presented. This patient received omeprazole at a daily dose of 40-60 mg for 4 years as treatment for a gastro-oesophagal reflux complicated by peptic oesophagitis. Seric vitamin B12 was dramatically decreased at 80 pmol L-1.
View Article and Find Full Text PDFBackground/aims: Resection and liver transplantation are currently considered as the most useful treatments for hepatocellular carcinoma. However, transcatheter oily chemoembolization may be favourably compared with these two surgical treatments in patients with anatomically operable tumors.
Methods: Between 1985 and 1991, 122 patients with an Okuda stage I tumor were hospitalized in two French hospitals.
Gastroenterol Clin Biol
October 1996
Objectives: It was recently demonstrated that low-dose polyethylene glycol 4000 (PEG) electrolyte lavage solution, a colonic lavage solution used for cleaning the gut before colonic procedures, is effective in the treatment of chronic constipation. The aim of our study was to determine the digestive effects of low-dose PEG 4000 without electrolyte addition in healthy subjects.
Methods: Sixteen healthy male subjects with normal transit were included in a randomized controlled cross-over study.
Gastroenterol Clin Biol
April 1995
Background: In Western countries, only a small proportion of patients with hepatocellular carcinoma (HCC) can be treated with surgical resection. For other patients, locoregional management by transcatheter oily chemoembolization seems to be useful and warrants evaluation.
Methods: One hundred and twenty-seven French patients with an inoperable HCC were treated by transcatheter oily chemoembolization.