Publications by authors named "Bronagh Elmore"
Article Synopsis
- - Bacteria can hide inside host cells like macrophages to evade antibiotics, prompting research on using PLGA nanoparticles to deliver antibiotics to these intracellular bacteria.
- - Different sizes of Rhodamine-B conjugated PLGA nanoparticles were tested to see how well they were taken up by macrophages and epithelials, showing larger nanoparticles had better uptake by macrophages.
- - In tests against intracellular infections, larger antibiotic-loaded PLGA nanoparticles were more effective against K. pneumoniae, but not against S. aureus, suggesting that there's no universal solution for targeting all types of intracellular infections.
Klebsiella pneumoniae is recognized as an urgent threat to human health due to the increasing isolation of multidrug resistant strains. Hypervirulent strains are a major concern due to their ability to cause life-threating infections in healthy hosts. The type VI secretion system (T6SS) is widely implicated in microbial antagonism, and it mediates interactions with host eukaryotic cells in some cases.
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