[A clinical case of diagnosis of left ventricular noncompaction myocardium in a patient with infectious myocarditis].

The paper describes a rare clinical case involving primary cardiomyopathy (noncompaction of the left ventricular myocardium (NCLVM), infectious myocarditis, and, possibly, hypertrophic cardiomyopathy (HCM). Objective, laboratory instrumental, invasive examination (coronarography with right ventricular endomyocardial biopsy) of the patient and histological study of his heart biopsy revealed acute infectious myocarditis concurrent with NCLVM and, possibly, HCM. The detection of a rare abnormality as NCLVM necessitates a meticulous additional examination to identify other primary cardiomyopathies (including HCM).

[Ultrasonic endoscopic examination of the upper portion of the gastrointestinal tract].

Thirty-two patients with various diseases of the esophagus, stomach, and the adjacent organs (pancreas, liver and spleen) were examined to assess the potentialities of transesophageal ultrasonic endoscopy. The results were compared with the findings of fiber gastroscopy, x-ray and ultrasonic transabdominal examinations. Nineteen patients were examined for a malignant involvement of the esophageal and gastric wall and tumor progress at the site of anastomosis after combined treatment of gastric cancer.

Is superoxide an initiator of microsomal lipid peroxidation?

The effects of "pro-oxidant" quinones, doxorubicin, Fe(3+)-ADP-doxorubicin complex, and menadione, as well as of free radical scavengers possessing superoxide-dismuting activities, Fe(3+)-rutin and Cu(2+)-rutin, on superoxide production and lipid peroxidation in rat liver microsomes have been studied. All quinone compounds efficiently suppressed lucigenin-dependent chemiluminescence produced in NADPH-dependent microsomal lipid peroxidation, but exhibited different effects on cytochrome c reduction: doxorubicin and Fe(3+)-ADP-doxorubicin weakly inhibited and menadione enhanced it. In accord with previous findings, menadione inhibited malondialdehyde (MDA) formation in microsomes, while Fe3-ADP-doxorubicin enhanced it.

Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation.

Inhibitory effects of flavonoids rutin and quercetin on ferrous ion-dependent lipid peroxidation of lecithin liposomes and NADPH- and CCl4-dependent lipid peroxidation in rat liver microsomes were studied to elucidate the chelating and free radical scavenging activities of these compounds. The interaction of rutin with superoxide ion and ferrous ions and the reaction of quercetin with lipid peroxy radicals were also studied. Both flavonoids were significantly more effective inhibitors of iron ion-dependent lipid peroxidation systems due to chelating iron ions with the formation of inert iron complexes unable to initiate lipid peroxidation.

[X-ray fluorescent determination of iron, copper, zinc, bromine and rubidium in biopsies of the gastric mucosa].

A method of a combined use of fiber gastroscopy and x-ray fluorescent analysis was elaborated for a study of the chemical composition of the gastric mucosa. Fr, Cu, Zn, Br, and Rb concentrations were determined in gastric mucosa biopsy specimens obtained during fiber gastroscopy, using x-ray fluorescent analysis. The concentrations of trace elements in the gastric mucosa were determined in 13 healthy persons, in 23 patients with chronic mucosal atrophy, in 15--with gastric ulcer, and in 16--with polyps.

[Nasotracheal intubation with the use of fibroscopes].

The technique of nasotracheal intubation with a fibroscope in 139 patients is described. The advantages and disadvantages of the fibroscopes used, difficulties and complications associated with the technique and their reasons have been reviewed. It has been concluded that endoscopic intubation is an effective non-traumatic method and can be performed in complex cases by an experienced physician.

[Chelating and antiradical effect of rutin during peroxidation of lipids from microsomes and liposomes].

The antioxidative effect of rutin (vitamin P) on Fe2+-induced lipid peroxidation (LPO) in bovine heart microsomes and lecithin liposomes was studied. It was shown that the LPO-induced inhibition of microsomes and liposomes in the presence of rutin occurs via two mechanisms, i.e.