A method to assess the quality of additive manufacturing metal powders using the triboelectric charging concept.

A new method to assess the quality of additive manufacturing (AM) metal powders using the triboelectric charging concept is demonstrated using CpTi, Ti6Al4V, AlSi10Mg, IN 738, and SS 316L powders. For each powder tested, the surface chemical composition was first analyzed using X-ray photoelectron spectroscopy (XPS) to determine the composition of the passivation layer. Some modifications to the current GranuCharge™ setup, developed by GranuTools™, were then performed by incorporating a flow rate measuring tool to assess how tribocharging is affected as a function of flow rate.

Effect of Heat Treatment on the Microstructure and Mechanical Properties of 18Ni-300 Maraging Steel Produced by Additive-Subtractive Hybrid Manufacturing.

The present work investigates the effectiveness of two heat treatment cycles-solution treatment + aging (STA) and direct aging (DA)-on optimizing the microstructure and enhancing the mechanical properties of 18Ni-300 maraging steel (300 MS) produced by additive-subtractive hybrid manufacturing (ASHM). The STA treatment led to a fully martensitic microstructure with minor remnants of the cellular substructures associated with the solidification conditions in ASHM. DA resulted in some reverted austenite and partial dissolution of the cellular morphologies into shorter fragments.

[La mise en abyme d'un projet intergénérationnel de recherche: Un comité intergénérationnel comme processus et sujet de recherche].

Les projets de nature intergénérationnelle sont aujourd'hui hautement valorisés par les décideurs publics et les responsables académiques. La pandémie de COVID-19 a fait ressurgir l'importance des relations entre les générations et des projets intergénérationnels ancrés dans la communauté. Cet article présente les résultats d'une étude visant à faire travailler ensemble des personnes aînées et des jeunes adultes au sein d'un projet intergénérationnel ancré dans la communauté.

In Envelope Additive/Subtractive Manufacturing and Thermal Post-Processing of Inconel 718.

This study investigated the application of an in envelope additive/subtractive (LPBF) manufacturing method (Matsuura LUMEX-Avance-25) to fabricate IN718 benchmarking coupons. The coupons were then examined comprehensively for surface finish both with and without high-speed micro-machining. The microstructure of the manufactured IN718 coupons was investigated thoroughly in the as-fabricated condition and following three different standard and one non-standard post-processing heat treatments.

Shedding light on the circadian clock of the threespine stickleback.

The circadian clock is an internal timekeeping system shared by most organisms, and knowledge about its functional importance and evolution in natural environments is still needed. Here, we investigated the circadian clock of wild-caught threespine sticklebacks (Gasterosteus aculeatus) at the behavioural and molecular levels. Although their behaviour, ecology and evolution are well studied, information on their circadian rhythms are scarce.

Increased odds of having the metabolic syndrome with greater fat-free mass: counterintuitive results from the National Health and Nutrition Examination Survey database.

Background: It is well established that body composition influences metabolic health, but emerging data are conflicting with the largely purported idea that a large fat-free mass (FFM) has a protective effect on health. A potential explanation for these discrepancies is the way FFM is represented. The first objective is to determine the association between the metabolic syndrome (MetS) and FFM when the latter was represented in three different ways: 1-absolute FFM; 2-relative to squared height (FFMi); and 3-relative to body weight (FFM%).

Fetal Sex and Fetal Environment Interact to Alter Diameter, Myogenic Tone, and Contractile Response to Thromboxane Analog in Rat Umbilical Cord Vessels.

Fetal growth needs adequate blood perfusion from both sides of the placenta, on the maternal side through the uterine vessels and on the fetal side through the umbilical cord. In a model of intrauterine growth restriction (IUGR) induced by reduced blood volume expansion, uterine artery remodeling was blunted. The aim of this study is to determine if IUGR and fetus sex alter the functional and mechanical parameters of umbilical cord blood vessels.

Low-volume walking HIIT: Efficient strategy to improve physical capacity and reduce the risk of cardiovascular disease in older women with type 2 diabetes.

Background And Aims: To compare the effect of a low-volume walking high-intensity interval training (HIIT) to moderate-intensity continuous training (MICT) on risk of cardiovascular diseases and physical capacity in older women with type 2 diabetes (T2D).

Methods: Thirty inactive older women with T2D were randomized into either HIIT (75 min/week) or MICT (150 min/week). Cardiovascular risk profile (lipid profile; waist circumference and fat mass; resting, post-exercise and ambulatory blood pressure [BP]; VO peak; UKPDS score; ABC's) and physical capacity were assessed before and after a 12-week intervention.

The feasibility, reliability, and incremental value of two-dimensional speckle-tracking for the detection of significant coronary stenosis after treadmill stress echocardiography.

Background: Two-dimensional speckle-tracking echocardiography (STE) may help detect coronary artery disease (CAD) when combined with dobutamine stress echocardiography. However, few studies have explored STE with exercise stress echocardiography (ESE). We aimed to evaluate the feasibility, reliability, and incremental value of STE combined with treadmill ESE compared to treadmill ESE alone to detect CAD.

Fetal Cardiac Lipid Sensing Triggers an Early and Sex-related Metabolic Energy Switch in Intrauterine Growth Restriction.

Context: Intrauterine growth restriction (IUGR) is an immediate outcome of an adverse womb environment, exposing newborns to developing cardiometabolic disorders later in life.

Objective: This study investigates the cardiac metabolic consequences and underlying mechanism of energy expenditure in developing fetuses under conditions of IUGR.

Methods: Using an animal model of IUGR characterized by uteroplacental vascular insufficiency, mitochondrial function, gene profiling, lipidomic analysis, and transcriptional assay were determined in fetal cardiac tissue and cardiomyocytes.

Exercising for Insulin Sensitivity - Is There a Mechanistic Relationship With Quantitative Changes in Skeletal Muscle Mass?

Skeletal muscle (SM) tissue has been repetitively shown to play a major role in whole-body glucose homeostasis and overall metabolic health. Hence, SM hypertrophy through resistance training (RT) has been suggested to be favorable to glucose homeostasis in different populations, from young healthy to type 2 diabetic (T2D) individuals. While RT has been shown to contribute to improved metabolic health, including insulin sensitivity surrogates, in multiple studies, a universal understanding of a mechanistic explanation is currently lacking.

Thermo-Mechanical Modeling of Wire-Fed Electron Beam Additive Manufacturing.

The primary objective of this research was to develop a finite element model specifically designed for electron beam additive manufacturing (EBAM) of Ti-6Al-4V to understand metallurgical and mechanical aspects of the process. Multiple single-layer and 10-layer build Ti-6Al-4V samples were fabricated to validate the simulation results and ensure the reliability of the developed model. Thin wall plates of 3 mm thickness were used as substrates.

Obesity among postmenopausal women: what is the best anthropometric index to assess adiposity and success of weight-loss intervention?

Objectives: First, to establish the respective ability of body mass index (BMI), waist circumference (WC), and relative fat mass index (RFM), to estimate body fat (BF%) measured by DXA (DXA-BF%) and correctly identify postmenopausal women living with obesity (BF% > 35). Second, to identify the best indicator of successful weight-loss intervention in postmenopausal women living with obesity.

Methods: A total of 277 women (age: 59.

Physical activity energy expenditure and fat-free mass: relationship with metabolic syndrome in overweight or obese postmenopausal women.

Menopause transition is associated with detrimental changes in physical activity, body composition, and metabolic profile. Although physical activity energy expenditure (PAEE) is inversely associated with metabolic syndrome (MetS) in individuals at higher risk of cardiovascular disease, the association is unknown in low-risk individuals. The aim of the study was to investigate the association between PAEE and MetS (prevalence and severity) in inactive overweight or obese postmenopausal women with a low Framingham Risk Score (<10%).

A counterintuitive perspective for the role of fat-free mass in metabolic health.

Fat-free mass (FFM) has long been recognized to play a role in metabolic homeostasis. Over the years, it has become widely accepted by the scientific and general community alike that having a greater FFM can be protective for metabolic health. Hence, in the context of an aging population concurrently facing sarcopenia and an elevated incidence of metabolic diseases, substantial efforts are being made to study and develop interventions aiming to maintain or increase FFM.

Contribution of cellulosic fibre filter on atmosphere moisture content in laser powder bed fusion additive manufacturing.

Cellulosic materials are commonly used to manufacture the particulate filters used in laser powder bed fusion (LPBF) additive manufacturing (AM) equipment. An experimental approach has been used to calculate the moisture quantity and kinetics of sorption in a cellulosic filter at varying relative humidity (RH) levels. A prediction of the amount of moisture which can be theoretically held within a filter during storage before its use has been obtained.

Body mass index to predict fat mass and metabolic syndrome severity: should it really be specific to sex, age and ethnicity? A NHANES study (1999-2014).

Body mass index (BMI) is often criticised since it doesn't consider sex, age and ethnicity, which may affect the height scaling exponent of the equation. First, to identify specific height scaling exponents (α) based on sex, age and ethnicity. Second, to assess the performance of the current vs the proposed BMI equations (1) to predict total fat mass (TFM) and metabolic syndrome (MetS) severity and (2) to correctly identify obese individuals and those having MetS.

Differential clusters of modifiable risk factors for impaired fasting glucose impaired glucose tolerance in adults 50 years of age and older.

Background: The aim of this study was to identify modifiable risk factors associated with isolated impaired fasting glucose (IFG), isolate impaired glucose tolerance (IGT), or combined IFG-IGT in men and women aged 50 years and older.

Methods: Cross-sectional analyses were performed in 703 men and women aged between 50 and 80 years old from NHANES (2007-2008). Outcome variables: IFG and IGT (ADA 2003), estimated body composition, cardiometabolic profile, and socio-demographic, dietary, and lifestyle factors.

Low-Volume High-Intensity Interval Training (HIIT) versus Moderate-Intensity Continuous Training on Body Composition, Cardiometabolic Profile and Physical Capacity in Older Women.

Objectives: To compare the effect of low-volume HIIT to moderate-intensity aerobic training (MICT) on fat mass, cardiometabolic profile and physical capacity and confirm its feasibility in older women.

Methods: Inactive older women (60-75 years) were randomly assigned to 8 weeks of either HIIT (75 min/week; n=9) or MICT (150 min/week; n=9). Body composition, fasting metabolic profile, cardiovascular risk (Framingham score), and physical capacity (senior fitness test, VO2peak) were assessed before and after the intervention.

Profiling obesity phenotypes and trajectories in older adults of the Quebec NuAge cohort on nutrition and successful aging: A cluster analysis.

Obesity in older adults results from several interacting factors. Consequently, interventions have shown mitigated effects. We determined (a) the different subgroups of older adults with obesity based on clusters of associated comorbidities and (b) the trajectory of these clusters to assess their stability over 3 years and factors contributing to transitions.

Prevalence of the metabolic syndrome between 1999 and 2014 in the United States adult population and the impact of the 2007-2008 recession: an NHANES study.

To document changes in prevalence of the metabolic syndrome (MetS) in the United States adult population between 1999 and 2014 and to explore how variations in the dietary intakes explain changes in MetS prevalence and its components over time. A total of 38 541 individuals (aged 20-85 years; National Health and Nutrition Examination Survey 1999-2014) were studied. Outcome variables were MetS, waist circumference (WC), plasma high-density lipoprotein cholesterol (HDL-c), triglycerides, fasting glucose (FG) levels, resting systolic and diastolic blood pressure, dietary intakes (total daily energy, carbohydrates, proteins, fats, sodium, and alcohol intakes), the poverty income ratio (PIR) and sociodemographic data (age, sex, ethnicity).

Causal role of group B Streptococcus-induced acute chorioamnionitis in intrauterine growth retardation and cerebral palsy-like impairments.

Chorioamnionitis and intrauterine growth retardation (IUGR) are risk factors for cerebral palsy (CP). Common bacteria isolated in chorioamnionitis include group B Streptococcus (GBS) serotypes Ia and III. Little is known about the impact of placental inflammation induced by different bacteria, including different GBS strains.

A Comprehensive Approach to Powder Feedstock Characterization for Powder Bed Fusion Additive Manufacturing: A Case Study on AlSi7Mg.

In powder bed fusion additive manufacturing, the powder feedstock quality is of paramount importance; as the process relies on thin layers of powder being spread and selectively melted to manufacture 3D metallic components. Conventional powder quality assessments for additive manufacturing are limited to particle morphology, particle size distribution, apparent density and flowability. However, recent studies are highlighting that these techniques may not be the most appropriate.