Endovascular Versus External Targeted Temperature Management for Patients With Out-of-Hospital Cardiac Arrest: A Randomized, Controlled Study.

Background: Targeted temperature management is recommended after out-of-hospital cardiac arrest. Whether advanced internal cooling is superior to basic external cooling remains unknown. The aim of this multicenter, controlled trial was to evaluate the benefit of endovascular versus basic surface cooling.

Renal replacement therapy in patients with severe precapillary pulmonary hypertension with acute right heart failure.

Background: Renal replacement therapy has been suggested as a therapeutic option in the setting of acute right ventricular failure in patients with severe precapillary pulmonary hypertension. However, there are few data supporting this strategy.

Objectives: To describe the clinical course and the prognosis of pulmonary hypertensive patients undergoing renal replacement therapy in the setting of acute right heart failure.

Carboplatin: a new cause of severe type B lactic acidosis secondary to mitochondrial DNA damage.

In adults, type B lactic acidosis is rare and generally associated with a toxin, particularly metformin or antiretroviral nucleosides analogues. We report a case of lactic acidosis caused by carboplatin in a 50-year-old woman suffering from primary peritoneal carcinoma. She was admitted for severe lactic acidosis (pH 6.

Solitary hypothalamopituitary toxoplasmosis abscess in a patient with AIDS.

Toxoplasmosis is a disease caused by an obligate intracellular protozoal parasite, Toxoplasma gondii. It is the most common cause of focal brain lesions in patients with AIDS. The imaging features and endocrine disorders of CNS toxoplasmosis in patients with AIDS are reviewed.

Obstetrical Complications and Outcome in Two Families with Hereditary Angioedema due to Mutation in the F12 Gene.

Backgroud. Hereditary angioedema (HAE) is characterized by recurrent swelling of the skin, the abdomen (causing severe acute pain), and the airways. A recently discovered type caused by mutations in the factor XII gene (designated as HAE type III) occurs mainly in women.

[Disseminated tuberculosis with severe multi- organ failure in a patient with AIDS].

Introduction: Tuberculosis is the most common infectious complication in HIV infected patients. The incidence of tuberculosis and the proportion of disseminated disease increase with more severe immuno-suppression. Septic shock and multiple organ failure are uncommon but are of markedly bad prognostic significance.

Bronchoalveolar lavage cytological alveolar damage in patients with severe pneumonia.

Introduction: Histological examination of lung specimens from patients with pneumonia shows the presence of desquamated pneumocytes and erythrophages. We hypothesized that these modifications should also be present in bronchoalveolar lavage fluid (BAL) from patients with hospital-acquired pneumonia.

Methods: We conducted a prospective study in mechanically ventilated patients with clinical suspicion of pneumonia.

Accuracy of clinical presentation for differentiating bacterial from viral meningitis in adults: a multivariate approach.

Objective: To determine whether bacterial (BM) and viral (VM) meningitis can be differentiated based on initial clinical presentation.

Design And Setting: Retrospective cohort study in a medical emergency department and intensive care unit in a university hospital.

Patients: 144 adults, including 90 with confirmed BM and 54 unpretreated VM.

Usefulness of abdominal CT scan in severe peritoneal sepsis linked to primary peritonitis.

We report 2 cases of primary group A streptococcal peritonitis in which emergency abdominal CT scan ruled out a hollow viscus perforation, or necrosis, avoiding unnecessary laparotomy. These cases highlight the usefulness of abdominal CT scan and suggest that blind surgical exploration has no advantages.

Biventricular assist device for scombroid poisoning with refractory myocardial dysfunction: a bridge to recovery.

Unlabelled: We report the usefulness of biventricular mechanical circulatory support in a 36-yr-old woman with refractory myocardial dysfunction resulting from scombroid poisoning.

Design: Case report.

Setting: Medical and surgical university care units.