[Toxic melanoderma in chronic intoxication with trinitrotoluene].

Hyperkinetic atactic syndrome, an atypical neurologic disorder of a chemical origin, was reported in connection with trinitrotoluene-induced melanoderma. Decreased level of urinary 17-hydroxycorticoids stresses the failure of one biochemical link in melanin synthesis, but proves the same pathogenic origin of both melanopathy manifestations. Antioxidant therapy in the pathogenesis treatment of melanoderma is considered valuable.