Publications by authors named "Brittney M Snyder"

Introduction: Health agencies have called for research evaluating e-cigarette (EC) use in supporting prenatal smoking cessation. This study aimed to describe (1) the characteristics of smokers who begin using electronic cigarettes (ECs) during pregnancy, (2) how frequently smokers reduce or eliminate pre- and post-natal combustible cigarette (CC) use, and (3) the risk for neonatal health complications among smokers who initiate ECs during pregnancy.

Aims And Methods: Pregnant women using CCs exclusively during prepregnancy, who participated in a U.

View Article and Find Full Text PDF
Article Synopsis
  • The HEROS Study is a prospective, multicity research effort conducted from May 2020 to February 2021, aimed at understanding risk factors for SARS-CoV-2 infection and transmission, particularly among children and those with asthma or allergies.
  • The study utilized remote methods to enroll participants, who completed weekly surveys and nasal sampling, allowing researchers to gather data without in-person visits during the pandemic.
  • A total of 5598 individuals were involved, ensuring a comprehensive household-based analysis of infection and transmission dynamics related to COVID-19.
View Article and Find Full Text PDF

Background: Currently, there are no available tools to identify infants at the highest risk of significant morbidity and mortality from respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) who would benefit most from RSV prevention products. The objective was to develop and internally validate a personalized risk prediction tool for use among all newborns that uses readily available birth/postnatal data to predict RSV LRTI requiring intensive care unit (ICU) admission.

Methods: We conducted a population-based birth cohort study of infants born from 1995 to 2007, insured by the Tennessee Medicaid Program, and who did not receive RSV immunoprophylaxis during the first year of life.

View Article and Find Full Text PDF

Newborn metabolite perturbations may identify potential biomarkers or mechanisms underlying adverse, smoking-related childhood health outcomes. We assessed associations between third-trimester smoking and newborn metabolite concentrations using the Tennessee Pregnancy Risk Assessment Monitoring System (PRAMS, 2009-2019) as the discovery cohort and INSPIRE (2012-2014) as the replication cohort. Children were linked to newborn screening metabolic data (33 metabolites).

View Article and Find Full Text PDF

Background: Research on health effects and potential harms of electronic cigarette (EC) use during pregnancy is limited. We sought to determine the risks of pregnancy EC use on pregnancy-related adverse birth outcomes and assess whether quitting ECs reduces the risks.

Methods: Women with singleton live births who participated in the US Pregnancy Risk Assessment Monitoring System (PRAMS) survey study 2016-2020 were classified into four mutually exclusive groups, by their use of ECs and combustible cigarettes (CCs) during pregnancy: non-use, EC only use, CC only use, and dual use.

View Article and Find Full Text PDF

Background: Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection (LRTI) in young children and is associated with subsequent recurrent wheezing illness and asthma (wheeze/asthma). RSV prevention may therefore reduce wheeze/asthma prevalence.

Objectives: We estimated the contribution of RSV LRTI and the impact of RSV prevention on recurrent wheeze/asthma in Mali.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates how maternal health characteristics affect newborn metabolic concentrations and, subsequently, child body mass index (BMI).
  • Using data from 3,492 infants across multiple birth cohorts, the research links maternal health information from questionnaires and medical records to newborn screening results.
  • Significant findings include higher pre-pregnancy BMI and maternal age correlating with specific metabolites, suggesting that maternal health may influence fetal growth and development through biological pathways.
View Article and Find Full Text PDF
Article Synopsis
  • The prevalence of obesity among US youths aged 2 to 19 was 19.3% from 2017 to 2018, and previous studies linked school lunches to increased obesity rates, prompting the Healthy, Hunger-Free Kids Act of 2010 (HHFKA) to enhance nutritional standards for school meals.
  • This study aimed to assess the impact of the HHFKA on youth body mass index (BMI) by analyzing data from a national cohort of children aged 5 to 18 over a period from January 2005 to March 2020.
  • Results indicated that after the HHFKA's implementation, there was a significant decrease in annual BMI z-scores, particularly among youths aged 12 to
View Article and Find Full Text PDF

Assessing the association of the newborn metabolic state with severity of subsequent respiratory tract infection may provide important insights on infection pathogenesis. In this multi-site birth cohort study, we identified newborn metabolites associated with lower respiratory tract infection (LRTI) in the first year of life in a discovery cohort and assessed for replication in two independent cohorts. Increased citrulline concentration was associated with decreased odds of LRTI (discovery cohort: aOR 0.

View Article and Find Full Text PDF
Article Synopsis
  • The HEROS study was a multi-city, 6-month research project conducted from May 2020 to February 2021, aiming to identify risk factors for SARS-CoV-2 infection and transmission, particularly among children and people with asthma and allergies.
  • It utilized remote methods to enroll and monitor participants, including weekly surveys and biweekly nasal samples, ensuring safety and compliance during the pandemic without any in-person interactions.
  • A total of 5,598 individuals were enrolled in the study, including children and their caregivers, showcasing a successful model for conducting large-scale observational research during challenging circumstances.
View Article and Find Full Text PDF
Article Synopsis
  • The study looks at how breastfeeding only can affect babies' health, especially with breathing problems and allergies.
  • Researchers checked data from nearly 2,000 babies to see how breastfeeding influenced their body’s defenses against sickness and the bacteria in their stomachs.
  • Results showed that breastfeeding has a good effect, helping to lower the chances of babies getting infections, asthma, and allergies as they grow up.
View Article and Find Full Text PDF
Article Synopsis
  • A cohort study was conducted on hospitalized patients using linked medical record data to create ICD criteria for identifying severe influenza cases.
  • The new criteria demonstrated an 80% positive predictive value when validated through medical records, indicating they reliably detect significant influenza hospitalizations.
  • The findings aim to improve evaluation of treatment strategies and inform public health policy regarding influenza interventions.
View Article and Find Full Text PDF
Article Synopsis
  • Scientists are studying how energy use in airway cells might affect children's lungs as they grow up, especially for those who wheeze or have asthma.
  • They looked at nasal cells from 15 boys at age 2 to see how well their cells used sugar and compared this to their health history.
  • The study found that kids who wheezed used less glucose in their cells, and higher blood sugar levels at age 1 seemed to help lower asthma risk by age 5.
View Article and Find Full Text PDF

Objective: Pregnant women with asthma have increased frequency of respiratory viral infections and exacerbations. Because of these risks, women with asthma may be subject to increased surveillance during pregnancy and may, therefore, be at increased risk of antibiotic receipt. The objective of this study was to assess the relationship between maternal asthma and outpatient prenatal antibiotic prescription fills to inform antibiotic stewardship.

View Article and Find Full Text PDF

Minor salivary gland biopsy (MSGB) is often used in patients lacking specific autoantibodies (seronegative patients) to confirm the presence of focal lymphocytic sialadenitis (FLS), which would suggest a diagnosis of Sjogren syndrome. There are no current guidelines indicating when to refer patients for MSGB. The objective of our study was to ascertain distinguishing clinical and laboratory features among individuals with sicca symptoms based on their serologic and histopathologic status, and to identify factors associated with FLS.

View Article and Find Full Text PDF

Background: Although a positive association has been established, it is unclear whether lower respiratory tract infections (LRTIs) with respiratory syncytial virus (RSV) cause chronic wheezing illnesses. If RSV-LRTI were causal, we would expect RSV-LRTI prevention to reduce the incidence of chronic wheezing illnesses in addition to reducing acute disease. We aimed to evaluate the strength of evidence for a causal effect of RSV-LRTI on subsequent chronic wheezing illness to inform public health expectations for RSV vaccines.

View Article and Find Full Text PDF

Aims: To evaluate the clinical utility of first and second trimester prenatal screening biomarkers for early pregnancy prediction of gestational diabetes mellitus (GDM) risk in nulliparous women.

Methods: We conducted a population-based cohort study of nulliparous women participating in the California Prenatal Screening Program from 2009 to 2011 (n = 105,379). GDM was ascertained from hospital discharge records or birth certificates.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionpnetlsubb3djkc95vd1lcig7uietc1bu): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once