Publications by authors named "Brittany Perija"
Article Synopsis
- Acquired haemophilia A (AHA) is a rare bleeding disorder caused by autoantibodies against factor VIII, with a population-based incidence of 1.78 cases per million per year found in a study in Manitoba, Canada.
- The study identified 34 patients over 15 years, most commonly presenting at an average age of 76, with 97% experiencing bleeding, often major, leading to delayed diagnoses and a need for haemostatic therapy.
- Treatment involved immunosuppressive therapy in 88% of cases, yielding an encouraging 79% remission rate, with relatively low treatment-related mortality and morbidity noted.
Background: Percutaneous closure of patent foramen ovale (PFO) in patients with cryptogenic stroke (CS) may reduce the risk of recurrent stroke. By performing closure only in those with high risk of recurrent PFO related strokes, patient selection may be improved. The Risk of Paradoxical Embolism (RoPE) score is a point-based index developed to estimate the probability that the index CS was attributable to patent foramen ovale.
View Article and Find Full Text PDFObjective: Iron supplementation in iron-deficiency anaemia is standard practice, but the benefits of iron supplementation in iron-deficient non-anaemic (IDNA) individuals remains controversial. Our objective is to identify the effects of iron therapy on fatigue and physical capacity in IDNA adults.
Design: Systematic review and meta-analysis of randomised controlled trials (RCTs).