Publications by authors named "Brittany Nave"
Article Synopsis
- Duchenne muscular dystrophy (DMD) leads to a gradual decline in functional muscle mass, which is replaced by fibrofatty tissue; this study aims to measure muscle mass using the Dcreatine (DCr) dilution method in DMD patients.
- A total of 92 DMD patients aged 4-25 participated in a 12-month study, where they ingested DCr and provided urine samples for analysis, revealing a significant correlation between muscle mass and measures of strength and functional capacity.
- The findings indicate that muscle mass decreases with age, especially in non-ambulant patients, suggesting the DCr dilution method could serve as a useful biomarker for monitoring disease progression in DMD and similar disorders.
