Hemorrhagic muscular metastasis of primary splenic hemangiosarcoma in a dog.

This report describes the presentation and management of an incidental primary splenic hemangiosarcoma with hemorrhagic muscle metastasis following an incisional biopsy of a temporalis mass in a dog. In the absence of clinical signs related to the primary splenic lesion, skeletal muscle metastasis of hemangiosarcoma could be misdiagnosed as isolated primary tumor, resulting in failure to provide an accurate prognosis and effective treatment of the primary tumor itself. A thorough diagnostic imaging workup in patients presenting with blood-filled subcutaneous or muscular masses is fundamental to rule out a primary visceral hemangiosarcoma.

Refractory shock, hypercoagulability, and multiorgan thrombosis associated with hypertrophic osteodystrophy in a dog.

Objective: To describe the clinical findings and case progression in a dog presenting with severe systemic inflammatory response, refractory shock, progressive metabolic acidosis, and respiratory failure that was ultimately diagnosed with hypertrophic osteodystrophy (HOD).

Case Summary: A 4-month-old male intact Mastiff presented with a 24-hour history of lethargy and generalized ostealgia. On examination, the dog was recumbent, febrile, and tachycardic with pain on palpation of the abdomen, right femur, and mandible.

Suspected benzodiazepine withdrawal-associated seizures in 3 young dogs undergoing mechanical ventilation.

Objective: To describe new onset of generalized seizures in 3 young dogs following cessation of a benzodiazepine-containing sedation protocol to facilitate mechanical ventilation (MV) for hypoxemia.

Series Summary: Three dogs under 5 months of age underwent MV due to severe hypoxemia. All 3 dogs were sedated with a constant rate infusion of benzodiazepines as part of their sedation protocol to facilitate MV.

Retrospective Evaluation of Clinical Bleeding in Dogs With Anticoagulant Rodenticide Toxicity-A Multi-Center Evaluation of 62 Cases (2010-2020).

Objective: To evaluate the most common locations of hemorrhage in dogs diagnosed with anticoagulant rodenticide intoxication.

Animals: Dogs presenting with hemorrhage secondary to anticoagulant rodenticide intoxication between at two university veterinary teaching hospitals.

Procedures: Medical records were searched from the years 2010 through 2020 and all records from dogs treated for hemorrhage secondary to anticoagulant rodenticide intoxication were reviewed.

Pathology in Practice.

In collaboration with the American College of Veterinary Pathologists.