Publications by authors named "Brittany Dean"
Factors influencing terrestriality in primates of the Americas and Madagascar.
Proc Natl Acad Sci U S A
October 2022
Among mammals, the order Primates is exceptional in having a high taxonomic richness in which the taxa are arboreal, semiterrestrial, or terrestrial. Although habitual terrestriality is pervasive among the apes and African and Asian monkeys (catarrhines), it is largely absent among monkeys of the Americas (platyrrhines), as well as galagos, lemurs, and lorises (strepsirrhines), which are mostly arboreal. Numerous ecological drivers and species-specific factors are suggested to set the conditions for an evolutionary shift from arboreality to terrestriality, and current environmental conditions may provide analogous scenarios to those transitional periods.
View Article and Find Full Text PDFThe coronavirus disease 2019 (COVID-19) pandemic has highlighted the urgent need for effective prophylactic vaccination to prevent the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Intranasal vaccination is an attractive strategy to prevent COVID-19 as the nasal mucosa represents the first-line barrier to SARS-CoV-2 entry. The current intramuscular vaccines elicit systemic immunity but not necessarily high-level mucosal immunity.
View Article and Find Full Text PDFArticle Synopsis
- - The COVID-19 pandemic has highlighted the need for effective vaccinations to combat the spread of SARS-CoV-2, with a focus on intranasal vaccines as they target the nasal mucosa, the first barrier to infection.
- - Current vaccines mainly provide systemic immunity via intramuscular injection, lacking the ability to activate mucosal defenses.
- - The AdCOVID vaccine, an intranasal adenovirus-based vaccine, successfully induces strong immune responses, including mucosal IgA and T cells, making it a promising candidate for COVID-19 prevention.
Context: Improving maternal nutrition and promoting alcohol abstinence during pregnancy are key to reducing subsequent economic and social impacts. However, antenatal nutrition and alcohol interventions are underused, partly because economic evidence to support investment is limited.
Objective: The purpose of this systematic literature review was to assess the extent to which economic evaluations have been applied to antenatal public health interventions, and implementation strategies addressing maternal nutrition and alcohol intake.