Comparison of titer results obtained using immediate spin one-dilution techniques to a reference method.

Background: Many transfusion services determine the titer of potentially incompatible plasma-containing products by performing a one-dilution titer at their selected titer threshold. This study compared the results of immediate spin (IS) one-dilution titers determined by three methods with a reference standard method.

Methods: Plasma-containing products from group A and O donors were titered using the participant's routine IS one-dilution titer method.