Atopic dermatitis (AD) and food allergies are 2 atopic conditions that tend to develop early in life. Their interrelationship has been a topic of controversy and many studies. The presence of atopic dermatitis in infancy and early childhood, particularly if severe, is a risk factor for the development of immunoglobulin E (IgE) -mediated food allergies.
View Article and Find Full Text PDFCurr Allergy Asthma Rep
March 2024
Purpose Of Review: This narrative review explores food allergy prevalence and natural history stratified by life stages, especially in context of evolving knowledge over the last few decades.
Recent Findings: The prevalence of food allergy remains highest in early childhood with common food triggers being cow's milk, soy, hen's egg, wheat, peanut, tree nuts, sesame, fish, and shellfish. This correlates with certain risk factors especially pertinent in the postnatal period which appear to predispose an individual to developing a food allergy.
J Allergy Clin Immunol Pract
August 2023
J Allergy Clin Immunol Pract
January 2023
Purpose Of Review: The goal of this review is to characterize health disparities impacting the recognition and treatment of anaphylaxis.
Recent Findings: Previous research has identified major health disparities related to atopic conditions including asthma, atopic dermatitis, and food allergies (FA); however, disparities related to anaphylaxis have yet to be examined in depth. We found widespread health disparities in the incidence and severity of anaphylaxis, as well as in the management of allergies (particularly food allergies) that place individuals at risk of anaphylaxis.
Objective: Objective structured clinical exams (OSCE) are used to train and assess resident foundational family-centered communication skills incorporating key stakeholders. In 2020 encounters were conducted virtually. We sought to compare standardized patient (SP) and family faculty (FF) assessment across OSCE and virtual OSCE (VOSCE) formats.
View Article and Find Full Text PDFThe increasing prevalence of food allergies is a growing public health problem. For children considered high risk of developing food allergy (particularly due to the presence of other food allergies or severe eczema), the evidence for the early introduction of allergenic foods, and in particular peanut and egg, is robust. In such cases, the consensus is clear that not only should such foods not be delayed, but that they should be introduced at approximately 4 to 6 months of age in order to minimize the risk of food allergy development.
View Article and Find Full Text PDFAnn Allergy Asthma Immunol
May 2021
Vaccines are one of the greatest medical innovations of all time, but there has been skepticism about them throughout history. Although initial concerns about scarcity increased public demand for COVID-19 vaccines, as supply meets demand, vaccine hesitancy may become a defining theme of the next stage of the COVID-19 pandemic.
View Article and Find Full Text PDFThe authors of this commentary discuss the “Peltzman Effect,” a phenomenon in which individuals respond to safety measures with a compensatory increase in risky behavior, and how it relates to the COVID-19 pandemic through “pandemic fatigue” and postvaccination behavior.
View Article and Find Full Text PDFCurr Opin Allergy Clin Immunol
December 2020
Purpose Of Review: Food oral immunotherapy (OIT) has emerged as way to mitigate serious allergic reactions including life-threatening anaphylaxis related to accidental ingestion. However, gastrointestinal-related adverse effects of OIT have been reported and are often cited as reasons for discontinuation of therapy. We summarize recent research on the prevalence of eosinophilic esophagitis (EoE) in patients undergoing OIT.
View Article and Find Full Text PDFA 12-year-old boy presented to the emergency department with findings concerning for multisystem inflammatory syndrome in children. After clinical stabilization following treatment with antibiotics, remdesivir, and anakinra, the patient was noted to have episodes of altered mentation. Video electroencephalogram revealed status epilepticus, which was subsequently controlled with antiepileptic medications.
View Article and Find Full Text PDFA 17-year-old obese male was admitted to the pediatric intensive care unit after presenting with fluid-responsive septic shock following 7 days of fever, gastrointestinal symptoms and neck pain. Initial workup was positive for SARS-CoV-2 and elevated troponin I and brain natriuretic peptide. Echocardiography and cardiac magnetic resonance imaging confirmed acute myocarditis.
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