Introduction: Several life-threatening conditions associated with thrombosis include acute ischemic stroke (AIS), acute myocardial infarction (AMI), and acute pulmonary embolism (PE). Fibrinolytics are among the treatment algorithms for these conditions.
Objective: This narrative review provides emergency clinicians with an overview of fibrinolytics for AIS, AMI, and PE in the emergency department (ED) setting.
Background: Junctional hemorrhage is a leading cause of battlefield death. Multiple FDA-approved junctional tourniquet (JTQ) models demonstrate effective hemorrhage control in laboratory settings. However, there are few real-world use cases within the literature.
View Article and Find Full Text PDFIntroduction: Multiple myeloma (MM) and its complications carry a high rate of morbidity and mortality.
Objective: This review evaluates MM and its complications, including presentation, diagnosis, and management in the emergency department (ED) based on current evidence.
Discussion: MM is the second most common hematologic cancer and associated with monoclonal plasma cell proliferation.
Introduction: High-pressure injection injury is a serious condition that carries with it a high rate of morbidity and mortality.
Objective: This review highlights the pearls and pitfalls of high-pressure injection injury, including presentation, diagnosis, and management in the emergency department (ED) based on current evidence.
Discussion: High-pressure injection injuries are uncommon entities caused by powerful jet streams, typically from high-pressure liquid spraying machines capable of generating forces exceeding thousands of pounds per square inch (psi).
Introduction: Airway management including endotracheal intubation (ETI) is a key skill for emergency clinicians. Therefore, it is important for emergency clinicians to be aware of the current evidence regarding the identification and management of patients requiring ETI.
Objective: This paper evaluates key evidence-based updates concerning ETI for the emergency clinician.
Introduction: Ectopic pregnancy is a serious condition that can have significant morbidity and mortality.
Objective: This review highlights the pearls and pitfalls of ectopic pregnancy, including presentation, diagnosis, and management in the emergency department (ED) based on current evidence.
Discussion: Ectopic pregnancy is a pregnancy that implants outside the normal uterine cavity.
Background: Vital signs are an essential component of the emergency department (ED) assessment. Vital sign abnormalities are associated with adverse events in the ED setting and may indicate a risk of poor outcomes after ED discharge.
Clinical Question: What is the risk of adverse events among adult patients with abnormal vital signs at the time of ED discharge?
Evidence Review: Studies retrieved included 6 retrospective studies with adult patients discharged from the ED.
Background: Alcohol use disorder is associated with a variety of complications, including alcohol withdrawal syndrome (AWS), which may occur in those who decrease or stop alcohol consumption suddenly. AWS is associated with a range of signs and symptoms, which are most commonly treated with GABAergic medications.
Clinical Question: Is phenobarbital an effective treatment for AWS?
Evidence Review: Studies retrieved included two prospective, randomized, double-blind studies and three systematic reviews.