Publications by authors named "Briner R"

Gastroparesis is a pathology associating upper digestive symptoms, such as nausea and vomiting, with impaired gastric emptying in the absence of mechanical gastric or duodenal obstruction. It has a major impact on patients' quality of life, can lead to undernutrition, and -increases overall mortality. Several schools of thought converge on the hypothesis of a clinico--pathological spectrum of gastric neuro-muscular dysfunction encompassing gastroparesis and functional dyspepsia, in particular the subtype known as "postprandial distress syndrome".

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The authors present a historical analysis of the first neurosurgical service in Texas. Initially established as a subdivision within the Department of Surgery in the early 1900s, this service eventually evolved into the Department of Neurosurgery at the University of Texas Medical Branch (UTMB). The pivotal contributions of individual chiefs of neurosurgery throughout the years are highlighted, emphasizing their roles in shaping the growth of the neurosurgery division.

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High levels of methylmercury (MeHg) have been reported in Arctic marine biota, posing health risks to wildlife and human beings. Although MeHg concentrations of some Arctic species have been monitored for decades, the key environmental and ecological factors driving temporal trends of MeHg are largely unclear. We develop an ecosystem-based MeHg bioaccumulation model for the Beaufort Sea shelf (BSS) using the Ecotracer module of Ecopath with Ecosim, and apply the model to explore how MeHg toxicokinetics and food web trophodynamics affect bioaccumulation in the BSS food web.

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Yolk sac tumor (YST) is the most common prepubertal testicular tumor. It is considered a subtype of non-seminoma germ cell tumor (NSGCT) that is presumed to have an aggressive behavior with high malignant potential, thus requiring multimodality treatment with resection and chemotherapy. Treatment is curative for the majority of patients, even the ones with relapse after a few years.

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Current protocols recommend an initial assessment of acute kidney injury often extensive, not very useful in the majority of cases. A review of the literature allowed us to propose a management algorithm limiting these investigations integrating a « less is more » approach. The cornerstone of this algorithm is the urinary dipstick, inexpensive and easy to perform, used as a screening test.

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Evidence-based practice (EBP) in management is still in its infancy. Several studies suggest that managers in businesses and other organizations do not consult the scientific evidence when making decisions. To facilitate its uptake, we need to better understand practitioner attitudes and perceived barriers related to EBP.

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The authors present a unique case of a patient with communicating hydrocephalus and repeated ventriculoperitoneal shunt obstructions resulting from mucin-secreting enterogenous cell deposits at the cervicomedullary junction. Pathological examinations revealed that these cellular deposits lacked characteristic cystic architecture and the patient had no history of previous cyst with dissemination. Because of the repeated shunt obstructions and inability to surgically resect the lesion in its entirety, the authors elected radiation therapy to the cervicomedullary junction, encompassing the radiological abnormality.

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Background: Spinal surgery is increasingly being done in the outpatient setting. We reviewed our experience with inpatient and outpatient single-level anterior cervical discectomy and fusion with plating (ACDF+P).

Methods: All patients undergoing single-level anterior cervical discectomy and fusion with plating between August 2005 and May 2007 by two surgeons (RPB or JAF) were retrospectively reviewed.

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Health and safety legislation now requires organizations to undertake risk assessments for psychosocial hazards in the workplace. Despite this, there is relatively little guidance on what constitutes a psychosocial risk assessment and how one should be conducted. The approaches that do exist are not without problems.

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Work environments appear to have both positive and negative impacts on the psychological well-being of workers. This paper reviews a number of models and theories that have addressed this issue. First, those aspects of the psychological work environment, which are thought to be most relevant to well-being, are described.

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There is little evidence to suggest that the stress management interventions (SMIs) used in organizations are necessarily effective nor is it clear why, in principle, they should be. Why then do organizations introduce SMIs? A wide variety of reasons is apparent, many focusing on reducing the presumed costs of stress and the attractiveness of what appears to be a panacea-like intervention. The central aim of this study is to make the case for and outline an evidence-based approach to SMIs in which data gathered from initial assessments are used to make decisions about interventions.

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This paper critically reviews models of shiftwork and health and provides a historical overview of changes in the conceptualization of the association between them. Models are hypothetical and conceptually broad, becoming more so as they move away from linear, chronobiological to multidirectional, psychological conceptualizations. We attribute this tendency to the use of stress frameworks to explain the relationship between shiftwork and health.

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A 4-month-old male Quarter Horse was referred for evaluation of urinary incontinence. Physical examination revealed clinical signs consistent with cauda equina syndrome. Radiography revealed diskospondylitis of S2 through S4.

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Although there are strong popular beliefs about the value of a good night's sleep, there is very little documented evidence of day-to-day relations between sleep and well-being. In this study, covariations between sleep and both prior and subsequent daily states of well-being were studied in a healthy, employed sample. Thirty volunteers used pocket computers to complete a daily sleep diary and self-rating scales of mood, minor symptoms and social interaction experience.

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This paper considers the impact of working with computer-based systems in terms of mental workload and the well-being of operators. In particular, the paper focuses on issues of controllability in human-computer systems as they relate to operator stress. Through the adoption of a state control model of stress regulation, it becomes apparent that while general usability criteria are necessary for the design of controllable systems, they may not be sufficient to guarantee controllability.

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It is necessary to study the normal chemical contents in the human spinal cord in order to understand neurochemical changes that might occur under pathological conditions. In the present study, the comparative distribution of seven peptides was examined immunohistochemically in four levels (cervical, C; thoracic, T; lumbar, L; sacral, S) of the human spinal cord by means of the peroxidase-antiperoxidase technique. The peptides examined included bombesin (BOM), substance P (SP), cholecystokinin (CCK), somatostatin (SOM), methionine-enkephalin (M-ENK), vasoactive intestinal polypeptide (VIP), and thyrotropin releasing hormone (TRH).

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The human posterior columns are generally described as a myelinated fibre pathway. The present study demonstrates that more than 25% of the component axons are unmyelinated. Many of these unmyelinated axons are labelled by antibodies to calcitonin gene-related peptide (CGRP), a substance found in sensory cells, axons and terminals.

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The distribution of CGRP immunoreactivity in the cervical, thoracic, lumbar, and sacral levels of the human spinal cord was mapped at the light microscopic level with the aid of a rabbit-generated antiserum against human calcitonin gene-related peptide (CGRP). CGRP-positive fibers formed a dense plexus in lamina I, II, the reticulated region of lamina V, and the tract of Lissauer at all spinal cord levels. The distribution of fibers showed some variations dependent on the cord level analyzed.

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Experience with computed tomogram-guided stereotactic biopsy is described with special reference to technical considerations important to the application of the Brown-Roberts-Wells system in pediatric patients. Eleven procedures were performed in 9 patients aged 9 months to 16 years of age. In all cases, the lesion was either deep seated or related to deficit prone areas making open biopsy hazardous.

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A rapid and sensitive method for detecting amphetamine and methamphetamine in drug preparations and biological fluids has been developed. Amphetamine and methamphetamine in pharmaceutical and clandestine drug preparations can be easily screened from other contaminating drugs and readily identified by their fluorescence, with subsequent separation accomplished by TLC. The same general procedure can also be used to detect amphetamine and methamphetamine in human urine at concentrations of 0.

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