Publications by authors named "Brindha D"

Article Synopsis
  • The study addresses the challenges of traditional manual urinalysis for kidney disease by introducing an advanced deep learning model using the YOLOv5 architecture, which improves speed and reduces data requirements compared to conventional methods.
  • The model detects six types of urine particles using a dataset of 5,376 microscopic images and employs a genetic algorithm to optimize hyperparameters, resulting in varying performances across the detected categories.
  • Among the YOLOv5 variants tested, YOLOv5l and YOLOv5x delivered the best overall performance, with mean average precision (mAP) values of 85.8% and 85.4%, respectively, while mycete detection achieved the highest mAP of 97
View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on synthesizing non-toxic zinc oxide nanoparticles (ZnO NPs) from marine algae (Sargassum polycystum) due to concerns about their environmental impact and lack of regulation.* -
  • Characterization methods showed that these nanoparticles are rod-shaped with an average diameter of about 100 nm and exhibit specific crystal properties.* -
  • Toxicity tests using zebra fish larvae indicated that ZnO NPs caused developmental delays, increased deformities, oxidative stress, and changes in cellular activity, highlighting potential risks even with green synthesis methods.*
View Article and Find Full Text PDF

An area of medical science, that is, gaining prominence, is DNA sequencing. Genetic mutations responsible for the disease have been detected using DNA sequencing. The research is focusing on pattern identification methodologies for dealing with DNA-sequencing problems relating to various applications.

View Article and Find Full Text PDF

Parkinsons disease (PD) is the second most neurodegenerative disease, which results in gradual loss of movements. To diagnose PD in a clinical setting, clinicians generally use clinical manifestations like motor and non-motor symptoms and rate the severity based on unified Parkinsons disease rating scale (UPDRS). Such clinical assessment largely depends on the expertise and experience of the clinicians and it is subjective leading to variation in assessment between clinicians.

View Article and Find Full Text PDF

The anticancer activity of malvidin was studied in Dalton's lymphoma ascites (DLA)-induced solid and ascitic tumor mice models. Malvidin is a natural compound belonging to the family of O-methylated anthocyanidin and plays a predominant role in regulating both short- and long-term cellular activities. Animals were injected with DLA cells (1.

View Article and Find Full Text PDF

In the present study, we aimed to evaluate the anticancer effect of zinc oxide nanoparticles (ZnO-NPs) synthesized from Turbinaria conoides against a murine model of Dalton's lymphoma ascites (DLA). Nanoparticles were synthesized from the hydroethanolic extract of T. conoides (HETC).

View Article and Find Full Text PDF

A nonlinear stability theory is adopted to study centrifugal thermal convection in a magnetic-fluid-saturated and differentially heated porous layer placed in a zero-gravity environment. The axis of rotation of the layer is placed within its boundaries that leads to an alternating direction of the centrifugal body force. An analysis through the variational principles is made to find the unconditional and sharp nonlinear limits.

View Article and Find Full Text PDF

Medicinal plants play a key role in human health care. Frustration over the side effects of allopathic drugs has driven the medical world to take asylum in the plant kingdom for the treatment of various ailments. Euphorbia hirta belonging to the family of Euphorbiacae has been reported to possess antibacterial, antiviral, and anticancer activity.

View Article and Find Full Text PDF