Publications by authors named "Brinda R"

Background: Anxiety is common in pediatric patients, especially during vascular access procedures. Most well-studied affect and anxiety scales, including the Observation Scale of Behavioral Distress-Revised (OSBD-r), the modified Yale Preoperative Anxiety Scale (mYPAS), and the modified Induction Compliance Checklist (mICC), are too cumbersome for clinical use outside of research settings. HRAD± (Happy, Relaxed, Anxious, Distressed with yes/no to cooperation) is a clinically-efficient observational scale that evaluates pediatric procedural affect and cooperation.

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  • Hospitalized children and their caregivers often face anxiety, and using virtual reality (VR) can help reduce this stress, but the effectiveness of different software design elements remains unclear.
  • A study involving 202 participants evaluated how aspects like fictional environments and graphics quality influence feelings of awe and overall engagement with a custom VR application.
  • Results showed that fictional settings increased awe in pediatric patients, while high-quality graphics were more effective for adult caregivers, and all measures of awe positively correlated with engagement. Future research will look into additional VR design elements.
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  • Acute SARS-CoV-2 infections can lead to the production of various autoantibodies (AABs), even in mild cases, and these AABs may remain elevated in some individuals suffering from long COVID (LC).
  • A study using a large human protein array revealed that certain AAB targets were linked to the symptoms experienced by LC patients, particularly those affecting the nervous system.
  • Experiments showed that IgG from LC patients could induce pain, sensitivity, and balance issues in mice, highlighting the potential for targeting AABs in treatment for long COVID symptoms.
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The effectiveness of aqueous extracts of various medicinal plants in detoxification of aflatoxin B1 (AFB1) was tested in vitro by thin-layer chromatography and enzyme-linked immunosorbent assay (ELISA). Among the different plant extracts, the leaf extract of Vasaka (Adhatoda vasica Nees) showed the maximum degradation of AFB1 (≥ 98%) after incubation for 24h at 37 °C. The aflatoxin detoxifying activity of the A.

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Background: Aflatoxin contamination of various foodstuffs and agricultural commodities is a major problem worldwide. Several strategies have been reported for the detoxification of aflatoxins in contaminated foods and feeds, but all these methods have their own shortcomings. Traditional medicinal plants are potential sources of aflatoxin-detoxifying compounds.

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About 25 Ethnobotanical Plants belonging to 21 Angiospermic families used by the people of Anaimalai union for different types of diseases. These information's were collected from the tribal people of the union and reported for the first time. The great biodiversity of the vegetation particularly the medicinal plants are being unexplored.

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