Multiple giant cell formation - A consequence of type II pyrethroid intoxication.

Pesticides are the main remedy for pest eradication, but their use has been found to be harmful also to various non-target organisms. In this study, giant cell formation was observed in hepatocytes of experimental albino rats following two type II pyrethroid pesticdes, Cypermethrin and Beta-cyfluthrin. Histopathological examination was done for this purpose and the results revealed the formation of giant cells and polyploidy condition following intoxication of these experimental compounds with Beta-cyfluthrin, with an edge over, and Cypermethrin, probably due to structural differences.

Peripheral blood and bone marrow responses under stress of cypermethrin in albino rats.

Pyrethroids, commercially available pesticides, are greatly in use these days, and thus they carry considerable chances of contaminating various ecosystems. Haematotoxicity of cypermethrin, a broadly used type II pyrethroid, has been assessed in the present study. Selected parameters included determination of total RBC count, haemoglobin concentration (Hb conc.

Biochemical and histological changes in rat liver caused by cypermethrin and beta-cyfluthrin.

Cypermethrin and beta-cyfluthrin are two most widely used multipurpose pyrethroids. After determining their oral LD50 (416.98 mg kg-1 and 354.