Publications by authors named "Brigitte Steinbauer"
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Synopsis of recent research by authors named "Brigitte Steinbauer"
- Brigitte Steinbauer's research primarily focuses on the molecular mechanisms underlying cancer progression, particularly in breast and pancreatic cancers, highlighting the role of specific enzymes and signaling pathways in tumor metastasis and recurrence.
- In her study on breast cancer, Steinbauer identified acetyl-CoA carboxylase 1 (ACC1) as a crucial component in metastasis, revealing its increased phosphorylation in invading tumor cells in both murine and human models, suggesting potential therapeutic targets.
- Her investigations into pancreatic cancer emphasize the interplay between K-Ras mutations and cyclooxygenase-2 (COX-2) in tumor development, demonstrating how COX-2 influences tumor burden and gene expression, which could inform future treatment strategies against aggressive pancreatic neoplasms.
