Publications by authors named "Brigitte L Cochran"
This case discusses a 55-year-old patient who was evaluated at a dermatology outpatient clinic for a chronic, pruritic, and painful hyperkeratotic plaque located on her scalp vertex. Given the size of the plaque and its thick, yellow scales, an initial clinical diagnosis of seborrheic dermatitis was favored. However, after weeks of unsuccessful treatment with ketoconazole shampoo, topical fluocinolone 0.
View Article and Find Full Text PDFDupilumab, a systemic injectable biologic, can be prescribed to patients with atopic dermatitis who do not respond to topical treatments. Atopy can frequently subside by blocking inflammatory pathways, such as interleukin-4 (IL-4) and interleukin-13 (IL-13) in the immune system. Dupilumab is generally well-tolerated and mild; the most common adverse reactions listed are arthralgia, back pain, and conjunctivitis, which clears upon cessation or finalization of dupilumab therapy.
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- Phytophotodermatitis is a skin reaction caused by contact with plant chemicals (furocoumarins) and sunlight exposure, observed in a case study of a 34-year-old patient post-beach trip in Mexico.
- The patient's irregular hyperpigmented patch developed after handling lime during a margarita, linking the skin issue to both sun and citrus exposure.
- This case emphasizes the need for detailed patient history and examination to avoid misdiagnosis and inappropriate treatments for skin conditions that may appear similar.
Article Synopsis
- The patient had a noticeable mass in her armpit, which was identified as metastasis, and distinguishing it from a primary breast cancer was challenging.
- Key diagnostic tools like biopsy and specific immunohistochemical markers (S100 and Sox10) were vital in confirming the cancer's origin, highlighting the need for thorough assessments for melanoma patients, as breast metastases often lead to a worse prognosis.