Publications by authors named "Brigitte Bois-Joyeux"
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Synopsis of recent research by authors named "Brigitte Bois-Joyeux"
Brigitte Bois-Joyeux's research primarily focuses on the regulation of gene expression by the retinoic acid-related orphan receptor alpha (RORα), highlighting its roles in lipid metabolism, inflammation, and various developmental processes across different tissues.
Through studies involving HepG2 human hepatoma cells and cerebellar cultures, she has demonstrated RORα's influence on adipogenesis, Purkinje cell development, and the response to hypoxic conditions.
Her findings suggest that RORα not only regulates its own expression in response to environmental stressors like hypoxia but also impacts the expression of critical genes involved in coagulation and developmental processes, underscoring its potential therapeutic targets in metabolic and developmental disorders.
