Publications by authors named "Brigida Esteban"
Article Synopsis
- - A multicenter study in Spain from 2010 to 2019 assessed the incidence and management of aplastic anemia (AA), finding an incidence of 2.83 cases per million per year and a median age of diagnosis at 61 years, with severe cases requiring significant treatment.
- - The first-line treatment for AA commonly involved anti-thymocyte globulin along with cyclosporin A, and after 6 months, a response rate of 68.2% was observed, increasing over a median follow-up of nearly 4 years.
- - The overall 5-year survival rate was 73.6%, with better outcomes in younger patients, but a notable decline in older patients and moderate AA cases,
The effect of the polyvinylpyrrolidone and/or hydroxypropyl-beta-cyclodextrin on the photo-lability of aqueous solutions of the anti-inflammatory drug Naproxen was studied. Kinetic studies revealed that the presence of all of these additives reduced drug photodegradation. In all cases, the presence of the different additives elicited a change in the photomixture composition, being the alcoholic derivative the major photoproduct formed.
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