Publications by authors named "Bright Boakye"
Article Synopsis
- Erythrocyte membrane protein-1 (EMP-1) plays a crucial role in malaria by helping infected red blood cells attach to blood vessel walls; antibodies against it could offer protection against the disease.
- A study was conducted in Tamale, Ghana, involving 60 malaria-infected children and 30 control subjects, examining the presence of specific EMP-1 antibodies and related blood indices.
- Findings revealed a significant association between higher levels of EMP-1 antibodies and cases of uncomplicated malaria, with those lacking these antibodies more likely to suffer from severe anemia.
Background: Severe Plasmodium falciparum malarial anemia is still the principal cause of death in children in underdeveloped countries. An imbalance between proinflammatory and anti-inflammatory cytokines is associated with malaria progression. This study evaluated circulating levels of selected inflammatory cytokines among malaria-infected children in Ghana.
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