Publications by authors named "Bridget Bannerman-Chukualim"
Article Synopsis
- The metabolic network in a cell shows how small molecules change through chemical reactions, helped by enzymes and other factors.
- Scientists are learning more about these networks and how they work in different cells and conditions.
- The TrypanoCyc database helps study the metabolism of Trypanosoma brucei, a parasite that causes disease in humans and animals, and offers ways to visualize this complex information.
The number of paralogs of proteins involved in translation initiation is larger in trypanosomes than in yeasts or many metazoan and includes two poly(A) binding proteins, PABP1 and PABP2, and four eIF4E variants. In many cases, the paralogs are individually essential and are thus unlikely to have redundant functions although, as yet, distinct functions of different isoforms have not been determined. Here, trypanosome PABP1 and PABP2 have been further characterised.
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