The Effect of High-Dose Erythropoietin Perinatally on Retinal Function in School-Aged Children Born Extremely or Very Preterm.

Purpose: To investigate the long-term effects of high-dose recombinant human erythropoietin (rhEPO) administered during the perinatal period on retinal and visual function in children born extremely or very preterm.

Design: Randomized, double-blind clinical trial follow-up plus cohort study.

Methods:  Setting: Department of Ophthalmology, University Hospital Zurich, Zurich, Switzerland.

The Effect of Perinatal High-Dose Erythropoietin on Retinal Structural and Vascular Characteristics in Children Born Preterm.

Purpose: To study the long-term effects of perinatal high-dose recombinant human erythropoietin (rhEPO) on macular structural and vascular development in preterm children.

Design: Randomized, double-blind clinical trial follow-up plus cohort study.

Methods: Setting: Department of Ophthalmology, University Hospital Zurich, Zurich, Switzerland.

RAPID ONSET HYDROXYCHLOROQUINE TOXICITY.

Purpose: Hydroxychloroquine (HCQ) can cause irreversible damage to the retina, especially when taken over longer periods. The American Academy of Ophthalmology recommends a regimen for dosing, screening, and monitoring of patients treated with HCQ. We present an unusual case of a rapid development of severe HCQ-associated retinopathy already after 2 years after commencing HCQ treatment.