Objective: To review the pharmacology, efficacy, and safety of lesinurad and determine its role relative to other agents in the management of chronic gout.
Data Sources: A PubMed search (1946 to February 2018) using the terms lesinurad and RDEA594 was conducted to identify relevant articles.
Study Selection And Data Extraction: In vitro or in vivo evaluations of lesinurad published in the English language were eligible for inclusion.