Volumetric analysis of the aging auditory pathway using high resolution magnetic resonance histology.

Numerous shown consequences of age-related hearing loss have been unveiled; however, the relationship of the cortical and subcortical structures of the auditory pathway with aging is not well known. Investigations into neural structure analysis remain sparse due to difficulties of doing so in animal models; however, recent technological advances have been able to achieve a resolution adequate to perform such studies even in the small mouse. We utilize 12 members of the BXD family of recombinant inbred mice and aged separate cohorts.

Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3.

Hearing depends on precise synaptic transmission between cochlear inner hair cells and spiral ganglion neurons through afferent ribbon synapses. Neuroligins (Nlgns) facilitate synapse maturation in the brain, but they have gone unstudied in the cochlea. We report and knockout (KO) cochleae have fewer ribbon synapses and have impaired hearing.

Effect of Local Anesthetic Injections on Subjective Pain Scales in Pediatric Tonsillectomies: A Meta-analysis.

Objective: To assess the effect of local anesthetic injection on subjective pain scores for pediatric tonsillectomies on postoperative days (PODs) 0 and 1.

Data Sources: A comprehensive literature search was conducted with the PubMed, Embase, Web of Science, and Scopus databases.

Review Methods: A 2-researcher team following the PRISMA guidelines performed a systematic review and meta-analysis.

Anesthetic injections and analgesia use in pediatric post-tonsillectomy patients: A meta-analysis and systematic review.

Objective: To assess the effect of local anesthetic injection on post-operative analgesia and complications for pediatric tonsillectomies on post-operative day (POD) 0 and 1.

Methods: A 2-researcher team following the PRISMA guidelines performed a systematic review and meta-analysis. The databases Pubmed.

Management of Peritonsillar Abscess Within a Local Emergency Department: A Quality Analysis Study.

Objective: Peritonsillar abscess (PTA) is the most common deep space infection of the head and neck, affecting thousands of people annually with high treatment costs. The purpose of this project was to determine how in-network emergency departments (EDs) adhere to generally accepted guidelines regarding diagnosis and management of potential PTAs.

Methods: The authors performed a retrospective chart review to identify patients with PTA in five EDs in one year.

To Tube, or Not to Tube: Comparing Ventilation Techniques in Microlaryngeal Surgery.

Objectives/hypothesis: The objective of this study was to compare ventilation techniques utilized in microlaryngeal surgery.

Study Design: Retrospective cohort study.

Methods: Two-hundred surgeries performed from May 1, 2018 to March 1, 2020 and stratified as intubated, intermittently intubated (AAIV) or apneic.

nPEP protocol implementation and evaluation at a local US Crisis Center.

Non-occupational Post-Exposure Prophylaxis for HIV (nPEP) is recommended by the CDC for isolated exposures that pose "substantial risk" for HIV transmission. To combat multiple barriers to nPEP utilization, a comprehensive program was developed through the local community sexual assault provider. The purpose of this study was to evaluate nPEP protocol implementation.