Modulation of NGF by cortisol and the Stellate Ganglion Block - is this the missing link between memory consolidation and PTSD?

Post-Traumatic Stress Disorder (PTSD) is a common psychiatric disorder that is often associated with intrusive memories and deficits in declarative memory function. The neurobiology of this effect is complex. The report focus is to provide an overview of systems activated during stress and consequences of the activation as well as modulation of those effects.

Sympathetic system modulation to treat post-traumatic stress disorder (PTSD): a review of clinical evidence and neurobiology.

A review of clinical evidence and neurobiology on the effects of modulation of sympathetic system modulation to treat post-traumatic stress disorder (PTSD) is being presented . The review provides an overview of currently available treatments followed by efficacy of orally effective sympathetic blocking agents. The main focus of the review is the application of stellate ganglion blocks (SGBs) or a local anesthetic blockade of the sympathetic ganglion in the neck.