Publications by authors named "Brian Zaugg"

A 22-year-old woman with a history of high myopia (-8.00 -3.75 × 011, right eye; -6.

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Purpose: To determine whether there is a difference in efficiency during phacoemulsification when using the hybrid polymer tip compared with the metal balanced tip, as measured by cumulative dissipated energy (CDE) and total procedure time.

Setting: John A. Moran Eye Center, University of Utah, Salt Lake City, Utah.

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Purpose: To understand the role of ophthalmic viscosurgical devices (OVDs) in corneal incision contracture (CIC). Specifically, the aim was to evaluate with the tip of the phacoemulsification needle free of OVD, how various OVDs near the tip and sleeve may transmit thermal energy to the incision site.

Methods: A small chamber was filled with balanced saline solution (BSS), and a thin membrane was placed on the surface.

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Purpose: To determine the difference, if any, in grooving efficiency at various settings on the Whitestar Signature Pro phacoemulsification (phaco) system.

Methods: Cataractous lenses were simulated by exposing porcine lenses to formalin for 2 hours. A total of 120 lenses were analyzed at various power settings on both longitudinal and transversal handpieces.

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Purpose: To determine the actual vacuum pressure generated by the Oertli CataRhex 3 (Oertli), using an external measuring system.

Methods: The effective vacuum pressure created by the Oertli was measured with a pressure device that was continuous with the vacuum tubing system while closed to the external environment. Measurements were taken with the machine set to 300 and 500 mmHg at flow rates of 20, 35, and 50 mL/min and at bottle heights of 60, 80, and 100 cm.

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Purpose: To evaluate the effect of each of the tip sizes available for the Oertli CataRhex3 phacoemulsification machine on efficiency.

Methods: Porcine lenses were fixed in formalin for 2 hours, then cut into 3.0 mm cubes.

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Purpose: We assessed the effect of two lens cube sizes, three tip sizes, and two ultrasound (US) approaches on phacoemulsification efficiency and chatter.

Methods: After porcine lens nuclei were soaked in formalin, we divided them into cubes measuring 2.0 mm or 3.

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Article Synopsis
  • * The need for management guidelines was identified due to the novel corneal events arising from the treatment, leading to recommendations for collaboration between hematology/oncology professionals and eye care specialists.
  • * Key guidelines include regular eye exams for patients on belamaf, assessing corneal event severity, and using findings to guide treatment decisions, aiming to reduce ocular risks while maintaining treatment benefits.
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Article Synopsis
  • The authors emphasize the need to correct information in their previous article based on new FDA guidelines.
  • These corrections focus specifically on the drug belantamab Mafodotin (belamaf).
  • Recent changes to the FDA label impact how belamaf should be used and understood in clinical settings.
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Introduction: Patients with relapsed or refractory multiple myeloma (RRMM) represent an unmet clinical need. Belantamab mafodotin (belamaf; GSK2857916) is a first-in-class antibody-drug conjugate (ADC; or immunoconjugate) that delivers a cytotoxic payload, monomethyl auristatin F (MMAF), to myeloma cells. In the phase II DREAMM-2 study (NCT03525678), single-agent belamaf (2.

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Purpose: To evaluate longitudinal power settings for optimally efficient lens fragment removal, using the Centurion machine.

Setting: John A. Moran Eye Center, University of Utah, Salt Lake City, USA.

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Purpose: To measure the time to fragment removal and number of chatter events using various combinations of micropulse on times and off times (measured in milliseconds) of longitudinal ultrasound (US) using a venturi-based phacoemulsification system.

Setting: John A. Moran Eye Center, University of Utah, Salt Lake City, USA.

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Objective: Evaluate the effect of increasing ultrasound (US) power on chatter events and efficiency under both continuous and micropulse torsional US to reduce total cataract extraction times.

Design: In vitro laboratory study.

Methods: Porcine lens nuclei were incubated in formalin for 2 hours and then cut into 2-mm cubes.

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Purpose: The aim of this study was to determine optimal bottle height, vacuum, aspiration rate, and power settings of the Oertli CataRhex 3 phacoemulsification machine.

Methods: Porcine lens nuclei were hardened with formalin and cut into 2.0 mm cubes.

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Phacoemulsification, initially used in the late 1960s, continues to be the standard of care for cataract removal. An animal model was developed so that, in a controlled research setting, all the various machines, handpieces, tips, and settings could be investigated. As a general rule, the higher power, vacuum, and aspiration settings lead to optimally efficient phacoemulsification.

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Objective: To evaluate the optimum percent on time for the most efficient lens fragment removal using long-pulse torsional ultrasound (US).

Design: In vitro laboratory study.

Methods: Porcine lens nuclei were incubated in formalin for 2 hours and then cut into 2 mm cubes.

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Purpose: To determine optimal power settings on the Centurion Vision System during the grooving step in cataract surgery.

Methods: Intact porcine lenses hardened by formalin and placed in a chamber designed to simulate the anterior chamber of the eye were used to test longitudinal power at 40%, 70%, and 100% and torsional power at 0%. Flow rate was set at 40 mL/min.

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Objective: To compare relative efficiency and chatter of high aspiration and vacuum settings.

Design: In vitro laboratory study.

Methods: The John A.

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Idiopathic subepidermal calcinosis, also known as idiopathic calcinosis cutis, is a rare condition, which typically presents as a small, hard, subepithelial mass in the absence of systemic disease and trauma. We report on an atypical case of idiopathic calcinosis, which appeared in an otherwise healthy 61-year-old female along the tarsus of her right upper eyelid. The purpose of this case report is to demonstrate idiopathic calcinosis in an unusual location that is deep to the dermis and to discuss the vast differential diagnosis of this entity.

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Purpose: To examine the role of high vacuum and aspiration settings on efficiency using a transversal ultrasound (US) machine.

Setting: John A. Moran Eye Center Laboratory, University of Utah, Salt Lake City, Utah, USA.

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Purpose: To evaluate the optimum on-time setting for the most efficient removal of lens fragments using micropulse ultrasound (US) and Ellips FX transversal US in the Whitestar Signature Pro phacoemulsification machine.

Setting: John A. Moran Eye Center Laboratories, University of Utah, Salt Lake City, Utah, USA.

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Purpose: To determine optimum flow settings on the Centurion Vision System during the grooving step in cataract surgery.

Setting: John A. Moran Eye Center Laboratory, University of Utah, Salt Lake City, Utah, USA.

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Purpose: We identify long-term ocular sequelae subsequent to experimental blast exposure.

Methods: Male Long-Evans rats were exposed to 230 kPa side-on primary blast overpressure using a compressed air driven shock tube. Visual system function and structure were assessed for 8 weeks after exposure using optokinetic nystagmus and optical coherence tomography.

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Purpose: To assess the effect of varying levels of torsional power on phacoemulsification efficiency using an active-fluidics phacoemulsification platform with a 0.7 mm Sonata tip.

Setting: John A.

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