Publications by authors named "Brian T Kendrick"
Proc Natl Acad Sci U S A
March 2018
Article Synopsis
- Mutations in a specific gene lead to retinal detachment and photoreceptor cell degeneration due to issues in the retinal pigment epithelium (RPE).
- Canine studies showed widespread RPE-PR cell abnormalities, including retinal microdetachments that could be temporarily influenced by light exposure.
- Gene therapy using adeno-associated virus significantly improved RPE-PR interactions in affected canines, suggesting potential for similar treatments in humans with related vision disorders.
