Publications by authors named "Brian Ssenkumba"
Article Synopsis
- Venous thromboembolism (VTE) is a major cause of death in cancer patients, and the modified Khorana Risk Assessment Score (KRAS) is considered the top tool for assessing this risk.
- The study aimed to evaluate VTE risk among 100 cancer patients at the University of Calabar Teaching Hospital, analyzing their KRAS scores, soluble P-selectin levels, and thromboprophylaxis use.
- Results showed a significant number of participants at intermediate to high VTE risk, highlighting a lack of adherence to the Khorana score and underutilization of preventive measures in clinical practice.
Spectrum and Trends of Cancer in Southwestern Uganda from 2012 to 2021.
East Afr Health Res J
March 2024
Article Synopsis
- - Cancer is a major public health issue globally, especially in low and middle-income countries, with an increasing incidence in Uganda, where this study focuses on cancer trends in Southwestern Uganda from 2012 to 2021.
- - The study reviewed records from local medical facilities, totaling 4,197 cancer cases, with a median age of 52; notable findings include prostate cancer being the most common overall, while cervical cancer is the most prevalent among women, and retinoblastoma is the most frequent cancer in children.
- - The research indicates changing cancer patterns in Southwestern Uganda, with a rising number of diagnoses and a decrease in certain cancers, suggesting that better diagnostic and treatment capabilities may be influencing these trends.
Postpartum sepsis following caesarean sections among women in Uganda remains a risk. However, erratic supplies of standard dressing material make the risk a reality. Alternative wound dressing materials, therefore, remain a viable option.
View Article and Find Full Text PDFBackground: Prostate cancer is the leading cause of cancer-related death and the second most commonly diagnosed cancer among men in Uganda and most countries in Sub-Saharan Africa (SSA). The TMPRSS2-ERG fusion gene is the most common genetic alteration seen among prostate cancer patients. There are several contradicting reports about the association of ERG protein with poor prognosis, high PSA, and Gleason score.
View Article and Find Full Text PDFPurpose: The determination of the presence or absence of anaplasia in Wilms tumor is difficult sometimes creating diagnostic errors and is worsened by the use of neoadjuvant chemotherapy, which causes cellular alterations that may mimic anaplasia. This study described the histological features of Wilms tumor and their association with WT1 and p53 expression in archived specimens in South Western Uganda.
Patients And Methods: A series of 308 formalin-fixed paraffin-embedded tissue blocks belonging to 85 children were retrospectively recruited in the only public Histopathology laboratory in South Western Uganda.
Introduction: Gaucher disease is a rare autosomal recessive lysosomal storage disease with unknown prevalence in Africa and no record of the disease exists in Uganda.
Case Presentation: We report a case of a 12-year-old female, the last born of 6 from a family with no known familial disease who presented with non-neuronopathic Gaucher disease and superimposed malaria. The disease was initially misdiagnosed as hyperreactive malarial splenomegaly but was subsequently confirmed by examination of the bone marrow smear and core.
Introduction: Primary breast Burkitt lymphoma is extremely rare. Commonly endemic Burkitt lymphoma presents with abdominal, jaw, periorbital, or genitourinary mass.
Case Presentation: We report a case of a 16-year-old girl with rapidly enlarging left breast swelling associated with evening fevers.