Characterization of an x-ray source with a partitioned diamond-tungsten target for electronic brachytherapy with 3D beam directionality.

The Sculptura is a new high-dose-rate electronic brachytherapy system developed by Sensus Healthcare. By combining a steerable electron beam with a partitioned diamond-tungsten x-ray target, the x-ray source of the Sculptura is capable of producing highly anisotropic dose distributions, thus achieving true 3D beam directionality. This article reports the spectral and dosimetric characterization of the Sculptura x-ray source through a combination of measurements and Monte Carlo simulations for operating points between 50-100 kV.

Feasibility of external beam radiation therapy to deep-seated targets with kilovoltage x-rays.

Purpose: Radiation therapy to deep-seated targets is typically delivered with megavoltage x-ray beams generated by medical linear accelerators or Co sources. Here, we used computer simulations to design and optimize a lower energy kilovoltage x-ray source generating acceptable dose distributions to a deep-seated target.

Methods: The kilovoltage arc therapy (KVAT) x-ray source was designed to treat a 4-cm diameter target located at a 10-cm depth in a 40-cm diameter homogeneous cylindrical phantom.

The feasibility of an inverse geometry CT system with stationary source arrays.

Purpose: Inverse geometry computed tomography (IGCT) has been proposed as a new system architecture that combines a small detector with a large, distributed source. This geometry can suppress cone-beam artifacts, reduce scatter, and increase dose efficiency. However, the temporal resolution of IGCT is still limited by the gantry rotation time.

Feasibility of low-dose single-view 3D fiducial tracking concurrent with external beam delivery.

Purpose: In external-beam radiation therapy, existing on-board x-ray imaging chains orthogonal to the delivery beam cannot recover 3D target trajectories from a single view in real-time. This limits their utility for real-time motion management concurrent with beam delivery. To address this limitation, the authors propose a novel concept for on-board imaging based on the inverse-geometry Scanning-Beam Digital X-ray (SBDX) system and evaluate its feasibility for single-view 3D intradelivery fiducial tracking.

Comparison of entrance exposure and signal-to-noise ratio between an SBDX prototype and a wide-beam cardiac angiographic system.

The scanning-beam digital x-ray (SBDX) system uses an inverse geometry, narrow x-ray beam, and a 2-mm thick CdTe detector to improve the dose efficiency of the coronary angiographic procedure. Entrance exposure and large-area iodine signal-to-noise ratio (SNR) were measured with the SBDX prototype and compared to that of a clinical cardiac interventional system with image intensifier (II) and charge coupled device (CCD) camera (Philips H5000, MRC-200 x-ray tube, 72 kWp max). Phantoms were 18.

Scanning-beam digital x-ray (SBDX) technology for interventional and diagnostic cardiac angiography.

The scanning-beam digital x-ray (SBDX) system is designed for x-ray dose reduction in cardiac angiographic applications. Scatter reduction, efficient detection of primary x-rays, and an inverse beam geometry are the main components of the entrance dose reduction strategy. This paper reports the construction of an SBDX prototype, image reconstruction techniques, and measurements of spatial resolution and x-ray output.