Publications by authors named "Brian M Cieslewicz"
Article Synopsis
- Traditional bolus vaccine methods result in quick removal of vaccines from lymphoid tissues, but changes in how vaccines release antigens can enhance immune responses by mimicking natural infections.
- A new microneedle array patch (MIMIX) is designed for sustained vaccine delivery, embedding in the skin to release the influenza vaccine over 1-2 weeks, which improves immune response.
- In preclinical studies, the MIMIX approach showed faster immune responses, higher protection against different flu strains, and better overall effectiveness compared to regular intramuscular vaccinations.
