Publications by authors named "Brian Lora"

Article Synopsis
  • The study aims to understand whether the NIRS-vascular occlusion test (NIRS-VOT) shows differences in muscle metabolism based on sex and limb while also examining the impact of dietary capsaicin on metabolic estimates during the test.
  • Results showed significant differences in tissue desaturation rates (DeO) between limbs, with the quadriceps showing higher rates than the forearm, and between sexes, with women having higher DeO than men.
  • Capsaicin, while tested for its effects on muscle metabolism, did not produce clear changes, but interactions involving limb type, sex, and capsaicin were noted.
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Article Synopsis
  • Watching news can make people feel stressed, while Bob Ross's peaceful art can help people feel relaxed.
  • A study tested if watching Bob Ross would make people feel better and help their heart health compared to watching the news.
  • The results showed that watching Bob Ross improved mood by reducing feelings like anxiety and depression, but it didn't change heart health much.
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The public-health restrictions (e.g., remote learning, restricted access to facilities and dining halls) put in place by colleges to reduce the spread of COVID-19 resulted in forced isolation and modifications to health-related behaviors.

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Purpose: Heart rate variability (HRV) estimates the autonomic nervous system (ANS) influence on the heart and appears sex-specific. Sensory afferents exhibit sex-specificity; although, it is unknown if Capsaicin, an agonist for transient receptor potential vanilloid channel-1 (TRPV), alters cardiac ANS activity in a sex-dependent manner, which could be important given the predictive nature of HRV on risk of developing hypertension. Thus, we explored if there was sex-specificity in the effect of capsaicin on estimated cardiac ANS activity.

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Endothelial dysfunction is associated with cardiovascular disease development, nitric oxide (NO) deficiencies, and may be limb or sex-specific. Prior in vitro work indicated that the transient receptor potential vanilloid channel-1 (TRPV) is expressed in human arteries and the TRPV agonist capsaicin alters vasodilation in an endothelium-dependent manner; however, it is unknown if this translates in vivo or is limb or sex-dependent. Therefore, we sought to determine if there was limb or sex-specificity in the effect of capsaicin on microvascular function using near-infrared spectroscopy (NIRS)-derived tissue oxygen saturation (StO) reperfusion slope.

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