Publications by authors named "Brian Leung"

Biological invasions are a major threat to biodiversity, ecosystem functioning and nature's contributions to people worldwide. However, the effectiveness of invasive alien species (IAS) management measures and the progress toward achieving biodiversity targets remain uncertain due to limited and nonuniform data availability. Management success is usually assessed at a local level and documented in technical reports, often written in languages other than English, which makes such data notoriously difficult to collect at large geographic scales.

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Global targets aim to reverse biodiversity declines by 2050 but require knowledge of current trends and future projections under policy intervention. First, given uncertainty in measurement of current trends, we propose a risk framework, considering probability and magnitude of decline. While only 11 of 198 systems analyzed (taxonomic groups by country from the Living Planet Database) showed declining abundance with high certainty, 20% of systems had a 70% chance of strong declines.

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Article Synopsis
  • Many plant traits change with environmental factors, which indicates how plants adapt and how ecosystems might be affected by climate change.
  • The study uses Bayesian modeling to analyze the relationships between plant traits and environmental conditions for both native and non-native plants in Central Europe, assessing how these traits might shift by the year 2100.
  • The findings suggest that non-native species may experience greater trait changes compared to natives, with certain traits like height and leaf area expected to decline or increase differently based on whether the plants are woody or herbaceous.
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Background: There is limited research on real-world antidepressant utilization patterns in children and adolescents, particularly in non-western countries. We aimed to examine temporal trends of antidepressant prescribing practice among Chinese children and adolescents in Hong Kong over 14-year period.

Methods: This population-based study identified 9566 patients aged 5-17 years who had redeemed at least one antidepressant prescription within 2005-2018, using data from health-record database of Hong Kong public healthcare services.

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  • Some patients are missing their appointments at Dunedin Hospital, which is causing problems for both the hospital and their own health.
  • The hospital mostly uses letters and last-minute texts to notify patients, but many people don't receive their letters on time.
  • Patients think a better way to communicate, like using emails or letting them book their own appointments, could help them remember and make it to their visits.
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Background: Biological invasions threaten the functioning of ecosystems, biodiversity, and human well-being by degrading ecosystem services and eliciting massive economic costs. The European Union has historically been a hub for cultural development and global trade, and thus, has extensive opportunities for the introduction and spread of alien species. While reported costs of biological invasions to some member states have been recently assessed, ongoing knowledge gaps in taxonomic and spatio-temporal data suggest that these costs were considerably underestimated.

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Article Synopsis
  • Scientists are studying how wildlife and plant life (biodiversity) is changing around the world because of human activities.
  • They look at different measures of biodiversity, like how many species there are, how species change over time, and how similar or different species are in different places.
  • While some areas show both increases and decreases in species, research suggests that overall, the number of extinct species is going up faster than new species are forming globally.
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Behavioural responses to heat and desiccation stress in ectotherms are crucial for their survival in habitats where environmental temperatures are close to or even exceed their upper thermal limits. During low tide periods when pools in intertidal sediments heat up, a novel shell lifting behaviour (when hermit crabs crawl out of pools and lift up their shells) was observed in the hermit crab, Diogenes deflectomanus, on tropical sandy shores. On-shore measurements revealed that the hermit crabs left pools and lifted their shells predominantly when pool water exceeded 35.

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Unlabelled: The extent and impacts of biological invasions on biodiversity are largely shaped by an array of socio-economic and environmental factors, which exhibit high variation among countries. Yet, a global analysis of how these factors vary across countries is currently lacking. Here, we investigate how five broad, country-specific socio-economic and environmental indices (Governance, Trade, Environmental Performance, Lifestyle and Education, Innovation) explain country-level (1) established alien species (EAS) richness of eight taxonomic groups, and (2) proactive or reactive capacity to prevent and manage biological invasions and their impacts.

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Medullary thymic epithelial cells (mTECs) are key antigen-presenting cells mediating T cell tolerance to prevent harmful autoimmunity. mTECs both negatively select self-reactive T cells and promote the development of thymic regulatory T cells (tT) that mediate peripheral tolerance. The relative importance of these two mechanisms of thymic education to prevent autoimmunity is unclear.

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The international trade in exotic vertebrate pets provides key social and economic benefits but also drives associated ecological, ethical, and human health impacts. However, despite its clear importance, we currently lack a full understanding of the structure of the pet trade, hampering efforts to optimize its benefits while mitigating its negative effects. In the present article, we represent and review the structure of the pet trade as a network composed of different market actors (nodes) and trade flows (links).

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Communities are shaped by a variety of ecological and environmental processes, each acting at different spatial scales. Seminal research on rocky shores highlighted the effects of consumers as local determinants of primary productivity and community assembly. However, it is now clear that the species interactions shaping communities at local scales are themselves regulated by large-scale oceanographic processes that generate regional variation in resource availability.

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Recent analyses have reported catastrophic global declines in vertebrate populations. However, the distillation of many trends into a global mean index obscures the variation that can inform conservation measures and can be sensitive to analytical decisions. For example, previous analyses have estimated a mean vertebrate decline of more than 50% since 1970 (Living Planet Index).

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Article Synopsis
  • Understanding the future impacts of biological invasions is complex due to various environmental and socio-economic factors, making expert assessments vital in the absence of quantitative models.
  • An evaluation by 36 experts suggests that alien species invasions may rise by 20%-30%, posing significant threats to biodiversity, regardless of socioecological contexts.
  • Key drivers like transport, climate change, and socio-economic shifts will heavily influence these impacts, but proactive measures could lessen the consequences and contribute to global biodiversity goals.
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Avian influenza viruses occasionally infect and adapt to mammals, including humans. Swine are often described as "mixing vessels," being susceptible to both avian- and human-origin viruses, which allows the emergence of novel reassortants, such as the precursor to the 2009 H1N1 pandemic. ANP32 proteins are host factors that act as influenza virus polymerase cofactors.

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Due to the emergence of antibiotic resistance, antimicrobial photodynamic therapy (aPDT) has recently been demonstrated as a promising alternative to antibiotics to treat wound infections caused by multidrug-resistant (MDR) pathogens. This study aimed to evaluate the bacterial killing efficiency of aPDT mediated by methylene blue (MB) loaded thermosensitive hydrogels against methicillin-resistant Staphylococcus aureus (MRSA). Box-Behnken Design method was employed to investigate the impacts of the polymer compositions, Poloxamer 407, Poloxamer 188 and Carbopol 934P, on the gelation temperature (T) and release rate of MB.

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