Publications by authors named "Brian L Odle"
Comparison of pharmacists' scoring of fall risk to other fall risk assessments.
J Am Pharm Assoc (2003)
May 2022
Objectives: Given their professional education and participation within the health care system, pharmacists are ideal candidates to assess drug-associated fall risk for patients. The purpose of this investigation was to determine whether pharmacists can quantitatively differentiate individuals who reported falling within the previous year (fallers) from those who do not (nonfallers), and to compare the pharmacists' evaluation with 2 recently published fall risk assessments.
Design: Cross-sectional design of pharmacists' assessments of fall risk.
Opioids: A Review of Pharmacokinetics and Pharmacodynamics in Neonates, Infants, and Children.
Eur J Drug Metab Pharmacokinet
October 2019
Pain management in the pediatric population is complex for many reasons. Mild pain is usually managed quite well with oral acetaminophen or ibuprofen. Situations involving more severe pain often require the use of an opioid, which may be administered by many different routes, depending on clinical necessity.
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- * Participants who engaged in treadmill gait training with visual feedback showed a significant reduction in their Quantitative Drug Index (QDI) scores, indicating a decrease in drug-associated fall risk, compared to those who trained without feedback.
- * The results also suggested that age played a significant role in how QDI scores changed, highlighting the need for further research to identify which specific drugs or classes contributed to this improvement.
Background: Guidelines recommend the use of multiple pharmacologic agents and/or mechanical compressive devices for prevention of venous thromboembolism, but preference for any specific agent is no longer given in regard to safety or efficacy.
Objective: To compare postoperative bleeding rates in patients receiving enoxaparin, rivaroxaban, or aspirin for thromboprophylaxis after undergoing elective total hip arthroplasty or total knee arthroplasty.
Methods: This retrospective cohort analysis evaluated patients who received thromboprophylaxis with either enoxaparin, rivaroxaban, or aspirin.
Article Synopsis
- - The study investigates how drugs affect mobility and balance in older adults and suggests using a quantitative drug index (QDI) to better assess fall risk.
- - Fifty-seven community-dwelling older adults participated, and various tests were conducted to measure mobility, balance, and other factors, including drug intake and body mass index (BMI).
- - Findings revealed that age, BMI, and QDI significantly influenced mobility and balance test scores, with those taking higher-impact drugs performing worse than those taking low-impact drugs.
Echinacea is an herbal supplement commonly used as an immune system stimulant to prevent infections, such as the common cold or flu. Echinacea has been documented as a cyctochrome P450 (CYP) 3A4 inhibitor in vitro, but no formal studies have been conducted in humans. Etoposide is a cytotoxic, topoisomerase II inhibitor, chemotherapeutic agent used in the treatment of lung cancer.
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