Publications by authors named "Brian Kabuubi"
Article Synopsis
- The study investigates why the inner foreskin is more susceptible to HIV infection, focusing on the types of immune cells and cytokines present.
- Researchers analyzed foreskin tissue from 42 HIV-uninfected Ugandan men during circumcision, comparing CD4 T cell characteristics and cytokine levels between the inner and outer foreskin.
- Results showed that although outer foreskin cells had a higher rate of HIV entry, the inner foreskin contained more immune cells and inflammatory cytokines, suggesting it is a more favorable site for HIV acquisition.
Uganda is among the most HIV/AIDS-afflicted countries, and many HIV-infected persons live in remote areas with poor access to health care. The success of HIV care programs relies in part on patient monitoring using CD4 T cell counts. We conducted an evaluation of the point-of-care PIMA test using BD FACSCount as a gold standard.
View Article and Find Full Text PDFBackground: High retention (follow-up) rates improve the validity and statistical power of outcomes in longitudinal studies and the effectiveness of programs with prolonged administration of interventions. We assessed participant retention in a potential HIV vaccine trials population of fishing communities along Lake Victoria, Uganda.
Methods: In a community-based individual randomized trial, 662 participants aged 15-49 years were randomized to either mobile phone or physical contact tracing reminders and followed up at months 1, 2, 3, 6, 12 and 18 post-enrolment.