Publications by authors named "Brian J Bush"
Background: Infections have a poor prognosis in inpatients with cirrhosis. We aimed to determine regional variations in infections and their association with clinical outcomes in a global cohort of inpatients with cirrhosis.
Methods: In this prospective cohort study initiated by the CLEARED Consortium, we enrolled adults (aged >18 years) with cirrhosis who were non-electively admitted to 98 hospitals from 26 countries or regions across six continents between Nov 5, 2021, and Dec 10, 2022.
Article Synopsis
- The study investigates how country-level income affects mortality rates in hospitalized patients with cirrhosis, using data from 90 hospitals across 25 countries.
- Researchers collected data on patient demographics, disease severity, and treatment access while comparing outcomes based on the income classification of the countries involved.
- The primary outcomes focused on mortality and liver transplants during the hospital stay or within 30 days of discharge, aiming to identify predictors of death among cirrhotic patients in different income settings.