Synopsis of recent research by authors named "Brian E Lewis"
- Brian E Lewis's recent research focuses primarily on prostate cancer, with a particular emphasis on understanding racial disparities in the disease, especially between African American and Caucasian patients, through genetic and clinical analyses.
- Key findings from his studies include the identification of higher rates of CDK12 somatic mutations in African American men, as well as the clinical and molecular determinants influencing responses to innovative therapies like bipolar androgen therapy.
- Lewis's work also explores the genetic characteristics of metastatic prostate cancer to the central nervous system, highlighting the need for further investigation into the clinical impact of such metastases and the importance of genetic testing in improving patient outcomes.
