Pharmacokinetics and pharmacodynamics of intramuscular dexmedetomidine in dogs.

Objective: To determine the pharmacokinetics and pharmacodynamics of dexmedetomidine after IM administration in dogs.

Animals: 6 healthy adult purpose-bred dogs (3 males, 3 females) with a mean ± SD body weight of 25.2 ± 1.

Percutaneous microwave ablation of solitary presumptive pulmonary metastases in two dogs with appendicular osteosarcoma.

Objective: To describe percutaneous microwave ablation (MWA) of presumptive pulmonary metastases and the outcome of two dogs.

Animals: Two dogs with pulmonary lesions after treatment of spontaneously occurring appendicular osteosarcoma.

Study Design: Preliminary prospective clinical study.

Pharmacokinetics and pharmacodynamic effects of oral transmucosal and intravenous administration of dexmedetomidine in dogs.

Objective: To determine pharmacokinetic and pharmacodynamic properties of the injectable formulation of dexmedetomidine administered via the oral transmucosal (OTM) route to healthy dogs.

Animals: 6 healthy dogs.

Procedures: Injectable dexmedetomidine was administered IV (5 μg/kg) or via the OTM route (20 μg/kg) in a blinded, single-observer, randomized crossover study.

Use of a temporalis fascia transposition flap for ventral orbital stabilization after ventral orbitectomy in a dog.

Objective: To describe a novel surgical technique for ventral orbital reconstruction after ventral orbitectomy by using a temporalis fascia transposition flap.

Study Design: Case report.

Methods: A 7-year-old, spayed female Boston terrier was treated for multilobular osteochondrosarcoma arising from the cranial aspect of the left zygomatic arch, causing asymmetry of the face and mild exophthalmos of the left eye.

Efficacy of vaporized hydrogen peroxide for repeated sterilization of a single-use single-incision laparoscopic surgery port.

Objective: To determine the ability of vaporized hydrogen peroxide (VHP) to sterilize a single-use single-incision laparoscopic surgery port and its associated components after repeated simulated uses.

Study Design: Prospective in vitro experimental study.

Sample Population: Six single-use single-incision laparoscopic surgery ports with associated cannulas and insufflation tubing.

Forced-Air Warming Provides Better Control of Body Temperature in Porcine Surgical Patients.

Maintaining normothermia during porcine surgery is critical in ensuring subject welfare and recovery, reducing the risk of immune system compromise and surgical-site infection that can result from hypothermia. In humans, various methods of patient heating have been demonstrated to be useful, but less evaluation has been performed in techniques to prevent hypothermia perioperatively in pigs. We compared body temperature regulation during surgery before and after modification of the ambient temperature of the operating laboratories.