Publications by authors named "Brian Chapron"

Synopsis of recent research by authors named "Brian Chapron"

  • - Brian Chapron's recent research focuses on the pharmacokinetics and metabolism of drugs, particularly in pediatric populations and under pathological conditions such as Crohn's disease, highlighting the importance of accurately modeling drug interactions and bioavailability in these contexts.
  • - His studies include innovations in microphysiological systems that better replicate human organ function—such as kidney proximal tubules and the digestive system—which are essential for understanding drug metabolism and toxicity more accurately than traditional models.
  • - Additionally, Chapron has explored the genetics of drug metabolism, such as the role of CYP450 enzymes in drug interactions and vitamin D metabolism, contributing to a deeper understanding of individual variations in drug efficacy and safety.