Publications by authors named "Brian C McGuire"
Proc Natl Acad Sci U S A
May 2015
Article Synopsis
- The study examines how prolonged auditory stimulation (like constant noise) affects synaptic transmission in the cochlear nucleus of mice, leading to changes in synaptic properties.
- Mice exposed to noise showed a shift in synaptic behavior from strong depression to facilitation, demonstrating a homeostatic response where synapses adjust to maintain functionality under stress.
- Increased release sites at auditory nerve synapses helped restore communication fidelity, indicating that the brain adapts to auditory environments dynamically, which may have implications for hearing and perception after noise exposure.
