Inference on the Macroscopic Dynamics of Spiking Neurons.

The process of inference on networks of spiking neurons is essential to decipher the underlying mechanisms of brain computation and function. In this study, we conduct inference on parameters and dynamics of a mean-field approximation, simplifying the interactions of neurons. Estimating parameters of this class of generative model allows one to predict the system's dynamics and responses under changing inputs and, indeed, changing parameters.

Virtual brain twins: from basic neuroscience to clinical use.

Virtual brain twins are personalized, generative and adaptive brain models based on data from an individual's brain for scientific and clinical use. After a description of the key elements of virtual brain twins, we present the standard model for personalized whole-brain network models. The personalization is accomplished using a subject's brain imaging data by three means: (1) assemble cortical and subcortical areas in the subject-specific brain space; (2) directly map connectivity into the brain models, which can be generalized to other parameters; and (3) estimate relevant parameters through model inversion, typically using probabilistic machine learning.

Information overload in the context of COVID-19 pandemic: A repeated cross-sectional study.

Objectives: To assess the psychometric properties of the Coronavirus Information Overload scale (CovIO) and explore relationships between CovIO, its predictors and several health behaviours related to the COVID-19 pandemic, using Cancer Information Overload (CIO) scale results as a reference for comparison.

Methods: 2003 participants representative of the French adult population answered a self-administered questionnaire over two waves of polling (N= 1003, N= 1000). Respondents were randomized to fill CovIO or CIO scale.

[Sensory regulation disorders in child psychiatry].

Introduction: The processing of sensory information determines the development and growth of a child's abilities. Dysfunction in the processing of sensory stimuli can affect a child's behavior and can disrupt development. Sensory Regulation Disorders are frequently associated with Autism Spectrum Disorder (ASD), with the DSM-5 even including it as a diagnostic criterion.

Cancer information overload: Association between a brief version of the CIO scale and multiple cancer risk management behaviours.

Objectives: To demonstrate the best psychometric properties of the revised 5-item Cancer Information Overload (CIO) scale over the 10- and 8-item versions, for both English and French native speakers, and to explore the relationships between CIO and several cancer risk management behaviours in a large sample of caregivers, cancer survivors and healthy subjects.

Methods: 2809 participants (2568 from France, 241 from Australia) from two cancer survivor networks answered a self-administered questionnaire. After assessing the psychometric properties we studied the impact of CIO on health behaviours using multivariate logistic regression.

Intra-serous haematopoiesis.

The samples from pleural and pericardial effusion, in which immature haematopoietic cells had been identified cytologically, were re-examined. The results were then analysed along with the clinico-biological context and compared to published data. The aim was to determine the frequency, the type and the context of haematopoietic cell identification in pleural and pericardial fluid effusion.

Stereotaxic cytology of brain tumors. Review of an eight-year experience.

The cytologic diagnosis of 312 stereotaxic samplings performed on 292 patients suspected of having a brain tumor over an eight-year period was reviewed. At different depths of the stereotaxic track, biopsy specimens were secured for cytologic and histologic observations. Smears for cytology were stained both by the May-Grünwald-Giemsa and the Papanicolaou methods since each of them disclosed information complementary to the other.

[An evaluation of cerebrospinal fluid cytology in childhood leukaemias and lymphomas (author's transl)].

A cytological study of the cerebrospinal fluid was carried out on 72 children with leukaemia or lymphoma either at the onset or during the course of the disease. It proved extremely useful in revealing the presence of malignant cells in CSF's with normal cell count and in distinguishing with absolute certainty meningeal leukaemias from meningeal reactions of other origins, in particular the frequent histiocytic reactions to radiotherapy and/or chemotherapy. These "irritative" reactions are a reminder that iatrogenic damage to the central nervous system is a distinct possibility, and the modalities of treatment should perhaps be reconsidered when they attain a certain magnitude.