Nonlinear Quantum Photonics with a Tin-Vacancy Center Coupled to a One-Dimensional Diamond Waveguide.

Color centers integrated with nanophotonic devices have emerged as a compelling platform for quantum science and technology. Here, we integrate tin-vacancy centers in a diamond waveguide and investigate the interaction with light at the single-photon level in both reflection and transmission. We observe single-emitter-induced extinction of the transmitted light up to 25% and measure the nonlinear effect on the photon statistics.

Phase interference for probing topological fractional charge in a BiSbTeSe-based Josephson junction array.

Fractional charges can be induced by magnetic fluxes at the interface between a topological insulator (TI) and a type-II superconductor due to axion electrodynamics. In a Josephson junction array with a hole in the middle, these electronic states can have phase interference in an applied magnetic field with4×2πperiod, in addition to the 2interference of the Cooper pairs. Here, we test an experimental configuration for probing the fractional charge and report the observation of phase interference effect in superconducting arrays with a hole in the middle in both Au- and TI-based devices.

Solid-phase synthesis of a pentavalent GalNAc-containing glycopeptide (Tn antigen) representing the nephropathy-associated IgA hinge region.

Incomplete or aberrant glycosylation leading to Tn antigen (GalNAcalpha1-Ser/Thr) expression on human glycoproteins is strongly associated with human pathological conditions, including tumors, certain autoimmune diseases, such as the idiopathic IgA nephropathy, and may modulate immune homeostasis. In addition, the Tn antigen is highly expressed by certain pathogens and plays a role in host-pathogen interactions. To enable experimental approaches to study interactions of the Tn antigen with the immune system and analyze anti-Tn antibody responses in infection or disorders, we generated a Tn-expressing resource that can be used for high-throughput screening.

Serogroup C meningococcal osteomyelitis: a case report and review of the literature.

A rare case of a 7-year-old boy with acute hematogenous osteomyelitis caused by Neisseria meningitidis serogroup C is presented. The diagnosis of osteomyelitis was made by bone scintigraphy and a blood culture confirmed meningococci as the cause of the disease. Meningococcal osteomyelitis is exceptionally rare and to our knowledge, serogroup C meningococci have not been previously reported as a cause.

Status epilepticus: clinical analysis of a treatment protocol based on midazolam and phenytoin.

The efficacy of a combination of midazolam and phenytoin in treating generalized convulsive status epilepticus in children was studied retrospectively. The patient group comprised all patients admitted for generalized convulsive status epilepticus to the pediatric intensive care unit over 7 years. Patients treated according to the protocol were included (N = 122).

Excellent long-term outcome for survivors of apple peel atresia.

Background: Apple peel atresia is the rarest type of small bowel atresia. Because of its rare occurrence and high mortality rate, little is known about the long-term outcome of these children.

Methods: The patient charts, operative reports, and office notes of 15 children with apple peel atresia from 6 pediatric surgical centers in the Netherlands were reviewed.