Publications by authors named "Brett Curran"
Article Synopsis
- Ascending-to-descending aortic bypass is a repair method for complex aortic coarctation, showing low early complications, but long-term results were previously unclear.
- A study of 81 patients who had the procedure from 1985 to 2012 revealed 5, 10, and 20-year survival rates of 94%, 90%, and 85%, with no perioperative deaths and no significant complications related to the bypass.
- Overall, this technique is considered safe with excellent long-term outcomes, improving systemic hypertension, and does not interfere with future surgeries through the same chest incision.
Background: Vertebral body tethering (VBT) is a novel non-fusion technique for the management of scoliosis. Despite growing popularity, data concerning complications and thoracic surgery-related outcomes are lacking.
Methods: A single-institution retrospective review was conducted of patients who underwent VBT with video-assisted thoracic surgical exposure from 1/1/2015-3/1/2022.
Left Atrial to Left Ventricular Bypass Using a Valved Conduit for Mitral Prosthesis-Patient Mismatch.
Ann Thorac Surg Short Rep
December 2023
A 72-year-old woman presented with dyspnea 2 years after mitral valve replacement with a 25-mm Epic bioprosthesis. Exercise echocardiography revealed a mean transvalvular gradient of 16 mm Hg, consistent with functional mitral stenosis due to prosthesis-patient mismatch. Because of the anticipated difficulties with insertion of a larger prosthesis, we proceeded with bypass of the mitral valve using a left atrial to left ventricular valved conduit.
View Article and Find Full Text PDFBackground: Cytokines play a crucial role in the inflammatory response and are essential modulators of injury repair mechanisms. While minimally invasive operations have been shown to induce lower levels of cytokines compared to open thoracotomy, the inflammatory cytokine profile difference between video-assisted (VATS) and robotic-assisted thoracic surgery (RATS) techniques has yet to be elucidated.
Methods: In this prospective observational study of 45 patients undergoing RATS (n=30) or VATS (n=15) lung resection for malignancy, plasma levels of interleukin (IL)-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, vascular endothelial growth factor (VEGF), interferon (IFN)-γ, tumor necrosis factor (TNF)-α, monocyte chemo-attractant protein (MCP)-1, and endothelial growth factor (EGF) were measured before and after surgery via immunoassay.