Pharmacokinetics and pharmacodynamics of epsilon-aminocaproic acid in horses.

Objective: To determine the pharmacokinetics and pharmacodynamics of epsilon-aminocaproic acid (EACA), including the effects of EACA on coagulation and fibrinolysis in healthy horses.

Animals: 6 adult horses.

Procedures: Each horse received 3.

Culture-positive sepsis in neonatal camelids: 21 cases.

Background: There is limited literature on neonatal bacterial sepsis in New World (NW) camelids.

Hypothesis: Bacterial culture-positive crias have clinical differences based on the specific bacterial genera isolated.

Animals: Bacterial culture-positive NW camelid crias <21 days of age from 1990 to 2005 were included.

Evaluation of risk factors for development of catheter-associated jugular thrombophlebitis in horses: 50 cases (1993-1998).

Objective: To evaluate risk factors associated with development of catheter-associated jugular thrombophlebitis in hospitalized horses.

Design: Retrospective case-control study.

Animals: 50 horses with thrombophlebitis and 100 control horses.

Efficacy of Saccharomyces boulardii for treatment of horses with acute enterocolitis.

Objective: To evaluate the viability of Saccharomyces boulardii after PO administration in clinically normal horses and its efficacy as a treatment for horses with acute enterocolitis.

Design: Prospective study.

Animals: 5 clinically normal horses and 14 horses with acute enterocolitis.

Idiopathic pericarditis and cardiac tamponade in two cows.

Idiopathic pericarditis is an uncommon diagnosis in cattle with cardiac tamponade. Two cows were examined for clinical signs of right-sided congestive heart failure, including tachycardia, venous distention, and peripheral edema. Muffled heart sounds were detected in one of the cows.

Myonecrosis and cutaneous infarction associated with Salmonella serovar Infantum infection in a horse.

A 5-year-old Quarter Horse mare was referred for evaluation of oral ulcers, limb edema, weight loss, and weakness. There was marked diffuse swelling extending from the stifle region to the tarsal region of the left hind limb, and the horse had a left hind limb lameness. Firm swellings ranging from 2 to 15 cm in diameter and consisting of nodules, plaques, and discrete masses were palpated on both sides of the neck, over the right shoulder region, over the left elbow region, and over the left caudoventral aspect of the abdomen.

Critical peripartum disease in the mare.

The variety of diseases that occur in the peripartum mare require the examining veterinarian to evaluate the patient and the historical information carefullly so as to make an accurate diagnosis and begin appropriate therapy. An understanding of equine behavior, reproduction. mechanisms of shock,and gastrointestinal and reproductive physiology is requisite for accurate interpretation of the myriad of clinical signs of diseases present in this population.

Clinicopathologic evidence of disseminated intravascular coagulation in horses with acute colitis.

Objective: To detect subclinical disseminated intravascular coagulation (DIC) in horses with colitis and to determine any association between the diagnosis of subclinical DIC and outcome or occurrence of complications in horses with colitis.

Design: Prospective study.

Animals: 37 horses admitted to a veterinary teaching hospital for treatment of acute colitis.