Background: There are limited data regarding melanocyte density and distribution on sun-exposed skin of the head and neck, in particular, comparing morphology (hematoxylin-eosin [H&E] staining) and immunohistochemistry (Melan-A staining) on formalin-fixed tissue. Furthermore, comparisons of melanocyte density between distinct geographic populations have not been made using these methods. This information would be useful for physicians who use histologic criteria to diagnose and treat lentigo maligna.
View Article and Find Full Text PDFObjectives: To clarify clinicopathologic features and reconcile discrepancies in previous studies of folliculotropic mycosis fungoides (FMF).
Design: A single-center retrospective clinicopathologic study and a systematic review of FMF.
Setting: Tertiary referral center in the midwestern United States.
A case of cutaneous epithelioid angiosarcoma with anomalous CD30 expression, occurring after breast-conserving surgery and adjuvant irradiation, is reported. This seems to be the first such case reported. The differential diagnosis of CD30 epithelioid angiosarcoma is discussed.
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