Ultrasonic backscatter techniques are being developed to detect changes in bone caused by osteoporosis and other diseases. Backscatter measurements performed at peripheral skeletal sites such as the heel may place the interrogated region of bone tissue in the acoustic near field of the transducer. The purpose of this study is to investigate how measurements in the near field affect backscatter parameters used for ultrasonic bone assessment.
View Article and Find Full Text PDFObjective: The ultrasonic properties of scalp may be relevant to a variety of applications including transcranial ultrasound. However, there is no information about the ultrasonic properties of scalp available in the literature. While ultrasonic studies of skin from other anatomic regions have been previously reported, scalp tissue is generally thicker with a higher density of hair follicles, blood vessels and sebaceous glands.
View Article and Find Full Text PDFNumerous studies have performed in vitro ultrasonic measurements of cancellous bone in water to develop techniques for ultrasonic bone assessment. Because cancellous bone is a highly porous medium, ultrasonic reflections at the water-bone interface may be frequency dependent. The goal of this study was to investigate the effect of porosity on the frequency dependence of the reflected power.
View Article and Find Full Text PDFBrain is inhomogeneous due to its composition of different tissue types (gray and white matter), anatomical structures (e.g. thalamus and cerebellum), and cavities in the brain (ventricles).
View Article and Find Full Text PDFUltrasonic techniques are being developed to detect changes in cancellous bone caused by osteoporosis. The goal of this study was to test the relative in vivo performance of eight backscatter parameters developed over the last several years for ultrasonic bone assessment: apparent integrated backscatter (AIB), frequency slope of apparent backscatter (FSAB), frequency intercept of apparent backscatter (FIAB), normalized mean of the backscatter difference (nMBD), normalized slope of the backscatter difference (nSBD), normalized intercept of the backscatter difference (nIBD), normalized backscatter amplitude ratio (nBAR) and backscatter amplitude decay constant (BADC). Backscatter measurements were performed on the left and right femoral necks of 80 adult volunteers (age = 25 ± 11 y) using an imaging system equipped with a convex array transducer.
View Article and Find Full Text PDFIEEE Trans Ultrason Ferroelectr Freq Control
November 2021
Ultrasonic backscatter techniques may offer a useful approach for detecting changes in bone caused by osteoporosis. The goal of this study was to investigate how bone mineral density (BMD) and the microstructure of human cancellous bone affect three ultrasonic backscatter parameters that have been identified as potentially useful for ultrasonic bone assessment purposes: the apparent integrated backscatter (AIB), the frequency slope of apparent backscatter (FSAB), and the frequency intercept of apparent backscatter (FIAB). Ultrasonic measurements were performed with a 3.
View Article and Find Full Text PDFUltrasound Med Biol
September 2020
Ultrasonic backscatter techniques are being developed to detect changes in bone caused by osteoporosis. The present study introduces a new technique that measures the exponential decay in the amplitude of the backscatter signal quantified by a parameter called the backscatter amplitude decay constant (BADC). Measurements were performed on 54 specimens of cancellous bone from 14 human femurs using a 3.
View Article and Find Full Text PDFUltrasonic backscatter techniques are being developed to detect changes in cancellous bone caused by osteoporosis. One technique, called the backscatter difference technique, measures the power difference between two portions of a backscatter signal. The goal of the present study is to investigate how bone mineral density (BMD) and the microstructure of human cancellous bone influence four backscatter difference parameters: the normalized mean of the backscatter difference (nMBD) spectrum, the normalized slope of the backscatter difference spectrum, the normalized intercept of the backscatter difference spectrum, and the normalized backscatter amplitude ratio (nBAR).
View Article and Find Full Text PDFMaterials that simulate the ultrasonic properties of tissues are used widely for clinical and research purposes. However, relatively few materials are known to simulate the ultrasonic properties of cancellous bone. The goal of the present study was to investigate the suitability of using a polymer, open-cell rigid foam (OCRF) produced by Sawbones.
View Article and Find Full Text PDFA variety of ultrasonic techniques have been developed to detect changes in bone caused by osteoporosis. One approach, called the backscatter difference technique, analyzes the power difference between two different portions of a backscatter signal. Analysis gates with a certain delay τ, width τ, and separation τ are used to define portions of the backscatter signal for analysis.
View Article and Find Full Text PDFIEEE Trans Ultrason Ferroelectr Freq Control
December 2015
Ultrasonic backscatter techniques are being developed to diagnose osteoporosis. Tissues that lie between the transducer and the ultrasonically interrogated region of bone may produce errors in backscatter measurements. The goal of this study is to investigate the effects of intervening tissues on ultrasonic backscatter measurements of bone.
View Article and Find Full Text PDFBackscatter-difference measurements may be used to detect changes in bone caused by osteoporosis. The backscatter-difference technique measures the power difference between two portions of an ultrasonic backscatter signal. The goal of this study is to evaluate the feasibility of using an ultrasonic imaging system to perform backscatter-difference measurements of bone.
View Article and Find Full Text PDFUltrasonic backscatter techniques offer a promising new approach for detecting changes in bone caused by osteoporosis. However, several challenges impede clinical implementation of backscatter techniques. This study examines how the dense outer surface of bone (the cortex) affects backscatter measurements of interior regions of porous (cancellous) bone tissue.
View Article and Find Full Text PDFPhys Med Biol
February 2011
This study examines the frequency dependence of apparent ultrasonic backscatter from human cancellous bone as quantified by the apparent backscatter transfer function (ABTF). The term 'apparent' means that the backscatter signals are not compensated for the frequency-dependent effects of diffraction and attenuation. Backscatter measurements were performed in vitro on 22 specimens of bone using five transducers ranging in centre frequency from 1 to 10 MHz.
View Article and Find Full Text PDFJ Acoust Soc Am
December 2005
A restricted-bandwidth form of the Kramers-Kronig dispersion relations is applied to in vitro measurements of ultrasonic attenuation and dispersion properties of trabecular bone specimens from bovine tibia. The Kramers-Kronig analysis utilizes only experimentally measured properties and avoids extrapolation of ultrasonic properties beyond the known bandwidth. Compensation for the portions of the Kramers-Kronig integrals over the unknown bandwidth is partially achieved by the method of subtractions, where a subtraction frequency acts as an adjustable parameter.
View Article and Find Full Text PDFAm J Physiol Heart Circ Physiol
March 2003
A previous two-dimensional (2D) ultrasound study suggested that there is relaxation of the myocardium after defibrillation. The 2D study could not measure activity occurring within the first 33 ms after the shock, a period that may be critical for discriminating between shock- and excitation-induced relaxation. The objective of our study was to determine the left ventricular (LV) geometry during the first 33 ms after defibrillation.
View Article and Find Full Text PDFPhys Med Biol
September 2002
A number of investigators have performed in vitro measurements of cancellous bone to determine how various ultrasonic parameters depend on bone density and trabecular orientation. To facilitate handling and storage of bone specimens, the marrow is often removed prior to ultrasonic measurements. However, the assumption that marrow does not affect ultrasonic measurements at high frequencies (>1 MHz) has not been tested.
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