FAS and FAS-L expression by tumor cells and lymphocytes in breast carcinomas and their lymph node metastases.

FAS receptor (FAS, CD95) and FAS ligand (FAS-L, CD95-L) are complementary members of a particular apoptotic pathway that plays a major role in immune regulation. The activation of FAS-L may trigger cytotoxic mechanisms leading to the death of FAS-expressing cells. Tumor cells and tumor-infiltrating lymphocytes (TIL) may express FAS and FAS-L in various proportions, and their interplay may affect tumor behavior.

Fine-needle aspiration in the evaluation of nucleated red blood cells in the human placenta.

Objective: The purpose of this study was to evaluate the correlation between placental and umbilical cord nucleated red blood cell counts.

Study Design: Eighty placentas and their matched umbilical cord blood samples were collected prospectively immediately after delivery. In vitro fine-needle aspiration biopsy specimens were used to obtain placental tissue samples.