Publications by authors named "Brent A Kokubun"

Article Synopsis
  • Human small intestinal crypts are crucial for producing intestinal stem cells that can renew themselves and develop into an epithelial layer, which is important for studying intestinal disorders.
  • This study compared the viability of duodenal samples from surgical discards to those from preserved cadaveric donors, focusing on how different storage solutions and times affect their growth in culture.
  • Results showed that both cadaveric and surgical samples have the potential for successful isolation and culture of intestinal crypts, with surgical samples being viable up to 24 hours and cadaveric samples remaining viable for up to 144 hours post-storage.
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Background: The relationship between intra-articular injections and complication rates after total knee arthroplasty (TKA) remains controversial. This study's purpose was to determine the relationship between the number and timing of intra-articular injections with complications and outcomes after TKA from a single surgeon's database.

Methods: We retrospectively reviewed a series of 442 patients who underwent primary TKA from 2008-2015.

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HYPOTHESIS Patients with mild gallstone pancreatitis may undergo an early laparoscopic cholecystectomy (LC) within 48 hours of hospital admission without awaiting the normalization of pancreatic and liver enzyme levels. This may decrease the hospital stay without increasing morbidity or mortality and may minimize the unnecessary use of endoscopic retrograde cholangiopancreatography. DESIGN A retrospective review.

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Background: Prompt diagnosis and treatment of acute mesenteric ischemia (AMI) requires a high index of suspicion for timely management. Poor clinical outcomes and delays in surgical treatment are demonstrated even in modern clinical series. Recognition of exhaled volatile organic compounds (VOCs) specific to AMI may facilitate early detection and diagnosis and improve patient outcomes.

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